Volume 108, Issue 5, Pages (March 2002)

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Volume 108, Issue 5, Pages 583-586 (March 2002) Microbial Minimalism Nancy A. Moran Cell Volume 108, Issue 5, Pages 583-586 (March 2002) DOI: 10.1016/S0092-8674(02)00665-7

Figure 1 Size of Eubacterial Genomes in Relation to Number of intact ORFs (top) and % G+C Content in Genome (bottom) The red spots correspond to obligate pathogens, belonging to a variety of unrelated lineages. M. leprae contains inactivated genes not included in the tally of intact ORFs. Included are all eubacterial genomes available January 2002 in NCBI Entrez Genomes (http://www.ncbi.nlm.nih.gov:80/PMGifs/Genomes/eub_g.html), with numbers of intact ORFS taken from this annotation. Cell 2002 108, 583-586DOI: (10.1016/S0092-8674(02)00665-7)

Figure 2 Numbers of ORFs Assigned to Different Functional Categories for Fully Sequenced Genomes of Members of the β- and γ-Proteobacteria From top, they are Xylella fastidiosa, Yersinia pestis, Vibrio cholerae, Pseudomonas aeruginosa, Pasteurella multocida, Neisseria meningitidus, Haemophilus influenzae, Escherichia coli K12, and Buchnera aphidicola. Buchnera, the only organism in this group that is obligately associated with hosts and that has a highly reduced genome, shows reduced numbers of ORFs in all categories. Categories are those corresponding to the COGs database (Tatusov, R.L., Koonin, E.V., and Lipman, D.J., 1997, Science 278, 631-637, http://www.ncbi.nlm.nih.gov/COG/xindex.html). Cell 2002 108, 583-586DOI: (10.1016/S0092-8674(02)00665-7)