Right atrial area and right ventricular outflow tract akinetic length predict sustained tachyarrhythmia in repaired tetralogy of Fallot Beatrice Bonello,

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Right atrial area and right ventricular outflow tract akinetic length predict sustained tachyarrhythmia in repaired tetralogy of Fallot Beatrice Bonello, Aleksander Kempny, Anselm Uebing, Wei Li, Philip J. Kilner, Gerhard-Paul Diller, Dudley J. Pennell, Darryl F. Shore, Sabine Ernst, Michael A. Gatzoulis, Sonya V. Babu-Narayan International Journal of Cardiology Volume 168, Issue 4, Pages 3280-3286 (October 2013) DOI: 10.1016/j.ijcard.2013.04.048 Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Measurement of maximal RAAi (A) and RVOT akinetic region length (B). Measurements were made from balanced steady state free precession cine images. A shows an enlarged RA (33cm2/m2). B shows a 45mm non-contractile thin RVOT akinetic length. Abbreviations: LA: left atrium, LV: left ventricle, MPA: main pulmonary artery, RA: right atrium, RV: right ventricle. International Journal of Cardiology 2013 168, 3280-3286DOI: (10.1016/j.ijcard.2013.04.048) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Random survival forest analysis for predictors of atrial tachyarrhythmia. The relative importance of RAAi, age at the index CMR study, increased age at repair and the presence of more than mild TR for AA prediction during a median follow-up of 5.6years is shown. The upper and leftward location in the plot of RAAi illustrates its greater relative importance and the size of the circle the larger effect size. The dashed line is the cut-off for relevant predictors. Abbreviations: CMR: cardiac magnetic resonance imaging, RAAi: right atrium area indexed, TR: tricuspid regurgitation. International Journal of Cardiology 2013 168, 3280-3286DOI: (10.1016/j.ijcard.2013.04.048) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Kaplan–Meier curves illustrating freedom from atrial (A) and ventricular (B) tachyarrhythmias. A shows the time-to-atrial arrhythmia with respect to a RAAi cut-off value of 16cm2/m2. B shows the time-to-ventricular arrhythmia with respect to a RVOT akinetic region length cut-off value of 30mm. Abbreviations: n: number of patients, RAAi: maximal right atrium area indexed, RVOT: right ventricular outflow tract. International Journal of Cardiology 2013 168, 3280-3286DOI: (10.1016/j.ijcard.2013.04.048) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions