Hypersensitivity reactions to chemotherapy: Outcomes and safety of rapid desensitization in 413 cases  Mariana C. Castells, MD, PhD, Nichole M. Tennant, BA, David E. Sloane, MD, F. Ida Hsu, MD, Nora A. Barrett, MD, David I. Hong, MD, Tanya M. Laidlaw, MD, Henry J. Legere, MD, Samridhi N. Nallamshetty, MD, Ross I. Palis, MD, Jayanti J. Rao, MD, Suzanne T. Berlin, DO, Susana M. Campos, MD, Ursula A. Matulonis, MD  Journal of Allergy and Clinical Immunology  Volume 122, Issue 3, Pages 574-580 (September 2008) DOI: 10.1016/j.jaci.2008.02.044 Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Frequency of symptoms and signs during initial HSRs. Journal of Allergy and Clinical Immunology 2008 122, 574-580DOI: (10.1016/j.jaci.2008.02.044) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 A, Number and severity of reactions during desensitization. A mild reaction was defined as absence of chest pain, changes in blood pressure, dyspnea, oxygen, desaturation, or throat tightness. A severe reaction included 1 of these. B, Desensitization step at which reactions occurred (total number of reactions = 180). C, Desensitization course at which reactions recurred (total number of reactions = 135 [111 mild and 24 severe]). Journal of Allergy and Clinical Immunology 2008 122, 574-580DOI: (10.1016/j.jaci.2008.02.044) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions