Characterization of diffuse orbital mass using Apparent diffusion coefficient in 3-tesla MRI  Sahar M. ElKhamary, Alicia Galindo-Ferreiro, Laila AlGhafri,

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Characterization of diffuse orbital mass using Apparent diffusion coefficient in 3-tesla MRI  Sahar M. ElKhamary, Alicia Galindo-Ferreiro, Laila AlGhafri, Rajiv Khandekar, Silvana Artioli Schellini  European Journal of Radiology Open  Volume 5, Pages 52-57 (January 2018) DOI: 10.1016/j.ejro.2018.03.001 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 A, B: Marginal zone lymphoma, fat suppressed Axial T2WI and ADC image showed restricted pattern (ADC = 0.74 × 10−3 mm2/s) of the diffuse right orbital mass (thin white arrow) C,D: Orbital Inflammatory disease post contrast-enhanced fat suppressed Axial T1WI and ADC showed ill-defined retrobulbar fat infiltrative lesion with enlarged right lacrimal gland not responding to medical treatment (thick white arrow) with ADC value = 1.42 × 10−3 mm2/s. European Journal of Radiology Open 2018 5, 52-57DOI: (10.1016/j.ejro.2018.03.001) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 E,F Castleman's Disease, Plasma cell type plus mixed type – coronal fat suppressed T2WI and ADC images showing diffuse infiltrative pattern of the intermuscular orbital fat (thin white arrow) ADC = 0.78 × 10−3 sec/mm2 . G,H: Angiolymphoid Hyperplasia with Eosinophilia – coronal T1 non fat suppression, axial ADC image shows bilaterality of the lesions with focal Infiltrative pattern of the muscle and surrounding fat with lacrimal gland involvement (white dotted arrow) with ADC value = 1.25 × 10−3). European Journal of Radiology Open 2018 5, 52-57DOI: (10.1016/j.ejro.2018.03.001) Copyright © 2018 The Authors Terms and Conditions

Fig. 3 A,B: A: Comparison of ADC values from DW-MRI of benign and malignant histopathology confirmed diffuse orbital lesions and B: ADC values of diffuse orbital lymphoma and other lymphoproliferative lesions (B). European Journal of Radiology Open 2018 5, 52-57DOI: (10.1016/j.ejro.2018.03.001) Copyright © 2018 The Authors Terms and Conditions

Fig. 4 Area of receiver operating characteristic (ROC) curve (graphical plot of the sensitivity vs. 1–specificity) for using ADC values derived from DW MRI for cases with benign diffuse orbital mass. European Journal of Radiology Open 2018 5, 52-57DOI: (10.1016/j.ejro.2018.03.001) Copyright © 2018 The Authors Terms and Conditions