Osteoarthritis and Cartilage

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Osteoarthritis and Cartilage Platelet-rich plasma supplementation on hyaluronic acid/chondroitin sulfate hydrogel does not enhance the in vivo chondrogenesis in a rabbit osteochondral defect model B. Kim, H. Han, S. Lee, M. Lee Osteoarthritis and Cartilage Volume 24, (April 2016) DOI: 10.1016/j.joca.2016.01.324 Copyright © 2016 Terms and Conditions

Figure 1 (a) Osteochondral defect was made on the trochlear groove, and PRP embedded HA/CS gel was applied (b). Cartilage was regenerated at the defect site, but the small crater was remained in central area (c). Osteoarthritis and Cartilage 2016 24, DOI: (10.1016/j.joca.2016.01.324) Copyright © 2016 Terms and Conditions

Figure 2 Modified O'Driscoll's histologic scores for control and treatment groups at 12 weeks. The treatment groups that showed significant improvement compared with the control group at P < 0.05 are marked with asterisk. Osteoarthritis and Cartilage 2016 24, DOI: (10.1016/j.joca.2016.01.324) Copyright © 2016 Terms and Conditions

Figure 3 GAG contents of the regenerated tissue on the defect site. Asterisk, P < 0.05 for comparison between indicated groups. Osteoarthritis and Cartilage 2016 24, DOI: (10.1016/j.joca.2016.01.324) Copyright © 2016 Terms and Conditions