Imaging Phenotyping Using Radiomics to Predict Micropapillary Pattern within Lung Adenocarcinoma So Hee Song, MD, Hyunjin Park, PhD, Geewon Lee, MD,

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Imaging Phenotyping Using Radiomics to Predict Micropapillary Pattern within Lung Adenocarcinoma So Hee Song, MD, Hyunjin Park, PhD, Geewon Lee, MD, Ho Yun Lee, MD, PhD, Insuk Sohn, PhD, Hye Seung Kim, MS, Seung Hak Lee, MS, Ji Yun Jeong, MD, Jhingook Kim, MD, Kyung Soo Lee, MD, PhD, Young Mog Shim, MD Journal of Thoracic Oncology Volume 12, Issue 4, Pages 624-632 (April 2017) DOI: 10.1016/j.jtho.2016.11.2230 Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Schematic illustration of quantitative computed tomography features. 3D, three-dimensional. Journal of Thoracic Oncology 2017 12, 624-632DOI: (10.1016/j.jtho.2016.11.2230) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Decision curve analysis for the model using clinical features and the model with addition of radiomics features. The y axis measures the net benefit. The x axis shows the threshold probability. The red line represents the model combining radiomics and clinical features. The blue line represents the model using clinical features only. The thin gray line represents the assumption that all patients have lung adenocarcinoma with a micropapillary pattern. The black line represents the assumption that no patients have a micropapillary pattern. Journal of Thoracic Oncology 2017 12, 624-632DOI: (10.1016/j.jtho.2016.11.2230) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 Disease-free survival and overall survival curves according to different proportions of micropapillary pattern. Journal of Thoracic Oncology 2017 12, 624-632DOI: (10.1016/j.jtho.2016.11.2230) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 1 Journal of Thoracic Oncology 2017 12, 624-632DOI: (10.1016/j.jtho.2016.11.2230) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 2 Journal of Thoracic Oncology 2017 12, 624-632DOI: (10.1016/j.jtho.2016.11.2230) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions