Peter A. B. Wark, BMed, PhD, Fabio Bucchieri, MD, Sebastian L

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Presentation transcript:

IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations Peter A.B. Wark, BMed, PhD, Fabio Bucchieri, MD, Sebastian L. Johnston, MD, PhD, Peter G. Gibson, MBBS, Lynnsey Hamilton, BSci, PhD, Joanna Mimica, Giovanni Zummo, MD, Stephen T. Holgate, FRCP, John Attia, MD, PhD, Ammarin Thakkinstian, MD, Donna E. Davies, PhD Journal of Allergy and Clinical Immunology Volume 120, Issue 3, Pages 586-593 (September 2007) DOI: 10.1016/j.jaci.2007.04.046 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Serum IP-10 levels at presentation with acute asthma. Data are summarized by box plots: boxes represent the 25th and 75th percentiles, the central line represents the median, and solid circles represent outliers. Subjects with acute virus-induced asthma are represented by colored boxes, and those with non–virus-induced acute asthma are represented by open boxes. Those with acute virus-induced asthma had significantly increased median serum IP-10 levels (604 pg/mL [interquartile range, 450-1536.3]) compared with those with non–virus-induced acute asthma (167 pg/mL [interquartile range, 141.5-168], P < .001). Comparison between groups was analyzed by using the Mann-Whitney U test. Journal of Allergy and Clinical Immunology 2007 120, 586-593DOI: (10.1016/j.jaci.2007.04.046) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions