Survival and quality of life after extracorporeal life support for refractory cardiac arrest: A case series Amedeo Anselmi, MD, PhD, Erwan Flécher, MD,

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Survival and quality of life after extracorporeal life support for refractory cardiac arrest: A case series Amedeo Anselmi, MD, PhD, Erwan Flécher, MD, PhD, Hervé Corbineau, MD, Thierry Langanay, MD, Vincent Le Bouquin, MD, Marc Bedossa, MD, Alain Leguerrier, MD, Jean-Philippe Verhoye, MD, PhD, Vito Giovanni Ruggieri, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 150, Issue 4, Pages 947-954 (October 2015) DOI: 10.1016/j.jtcvs.2015.05.070 Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Study design. ECLS, Extracorporeal life support. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 947-954DOI: (10.1016/j.jtcvs.2015.05.070) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Actuarial (Kaplan–Meier) survival curve for patients receiving E-CPR for refractory cardiogenic shock; in-hospital mortality is included. The dashed lines indicate the confidence limits for the estimate. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 947-954DOI: (10.1016/j.jtcvs.2015.05.070) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Comparison of SF-36 scores observed among patients enrolled in our study (solid red line; E-CPR) with the corresponding SF-36 scores obtained from: patients who survived acute respiratory distress syndrome, through venovenous ECMO (CESAR study, ECMO cohort [14]; yellow dashed line; ECMO-CESAR); patients who survived postcardiotomy myocardial failure through veno-arterial ECLS ([13]; green dashed line; ECLS - postcardiotomy). Comparison with normal age- and gender-matched French population is shown (solid blue line; Control). PA, Physical Activity; MH, Mental Health; RL, Role Limitation; SA, Social Activity; PP, Physical Pain; VT, Vitality; GH, General Health; E-CPR, extracorporeal cardiopulmonary resuscitation; ECMO – CESAR, extracorporeal membrane oxygenation - conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure; ECLS, extracorporeal life support. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 947-954DOI: (10.1016/j.jtcvs.2015.05.070) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Survival curve for patients receiving extracorporeal cardiopulmonary resuscitation (follow-up: 15.6 ± 19.2 months). The Journal of Thoracic and Cardiovascular Surgery 2015 150, 947-954DOI: (10.1016/j.jtcvs.2015.05.070) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions