Loukia Yiangou, Alexander D.B. Ross, Kim Jee Goh, Ludovic Vallier 

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Presentation transcript:

Human Pluripotent Stem Cell-Derived Endoderm for Modeling Development and Clinical Applications  Loukia Yiangou, Alexander D.B. Ross, Kim Jee Goh, Ludovic Vallier  Cell Stem Cell  Volume 22, Issue 4, Pages 485-499 (April 2018) DOI: 10.1016/j.stem.2018.03.016 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Endoderm Derivatives Generated from hPSCs for Clinical Applications and Disease Modeling Schematic representation of hPSC differentiation into endoderm cell types and signaling pathways required for their generation. hPSC-derived endoderm cells can be used to model genetic disorders and infectious disease, to validate genes associated with disease and drug screening, and for cell therapy. Cell Stem Cell 2018 22, 485-499DOI: (10.1016/j.stem.2018.03.016) Copyright © 2018 Elsevier Inc. Terms and Conditions