Optimizing natural fertility: a committee opinion

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Optimizing natural fertility: a committee opinion Samantha Pfeifer, M.D., Samantha Butts, M.D., M.S.C.E., Gregory Fossum, M.D., Clarisa Gracia, M.D., M.S.C.E., Andrew La Barbera, Ph.D., Jennifer Mersereau, M.D., Randall Odem, M.D., Richard Paulson, M.D., Alan Penzias, M.D., Margareta Pisarska, M.D., Robert Rebar, M.D., Richard Reindollar, M.D., Mitchell Rosen, M.D., Jay Sandlow, M.D., Michael Vernon, Ph.D. Samantha Pfeifer, M.D., Samantha Butts, M.D., M.S.C.E., Gregory Fossum, M.D., Clarisa Gracia, M.D., M.S.C.E., Andrew La Barbera, Ph.D., Jennifer Mersereau, M.D., Randall Odem, M.D., Richard Paulson, M.D., Alan Penzias, M.D., Margareta Pisarska, M.D., Robert Rebar, M.D., Richard Reindollar, M.D., Mitchell Rosen, M.D., Jay Sandlow, M.D., Michael Vernon, Ph.D. Fertility and Sterility Volume 107, Issue 1, Pages 52-58 (January 2017) DOI: 10.1016/j.fertnstert.2016.09.029 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Pregnancy rate (per 1,000 women) in various populations at different times in history. Modified from Menken et al. (4). The 10 populations (in descending order at age 20 to 24) are Hutterites, marriages 1921–30 (solid triangles); Geneva bourgeoisie, husbands born 1600–49 (solid squares); Canada, marriages 1700–30 (solid circles); Normandy, marriages 1760–90 (open circles); Hutterites, marriages before 1921 (open squares); Tunis, marriages of Europeans 1840–59 (open triangles); Normandy, marriages 1674–1742 (solid circles); Norway, marriages 1874–76 (open squares); Iran, village marriages, 1940–50 (solid triangles); Geneva bourgeoisie, husbands born before 1600 (open circles). Fertility and Sterility 2017 107, 52-58DOI: (10.1016/j.fertnstert.2016.09.029) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Probability of pregnancy with a single act of intercourse. Modified from Dunson et al. (14). Fertility and Sterility 2017 107, 52-58DOI: (10.1016/j.fertnstert.2016.09.029) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Probability of pregnancy by cycle day, involving recurrent intercourse, by age. Data from Stanford and Dunson (16). Fertility and Sterility 2017 107, 52-58DOI: (10.1016/j.fertnstert.2016.09.029) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 4 Estimates of the probability of conception according to vaginal secretion observations on the day of intercourse. Data from Scarpa et al. (19). Fertility and Sterility 2017 107, 52-58DOI: (10.1016/j.fertnstert.2016.09.029) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions