Efficacy of Granulocyte Colony-Stimulating Factor and N-Acetylcysteine Therapies in Patients With Severe Alcoholic Hepatitis  Virendra Singh, Amarjit Keisham, Ashish Bhalla, Navneet Sharma, Ritesh Agarwal, Ratiram Sharma, Akash Singh  Clinical Gastroenterology and Hepatology  Volume 16, Issue 10, Pages 1650-1656.e2 (October 2018) DOI: 10.1016/j.cgh.2018.01.040 Copyright © 2018 AGA Institute Terms and Conditions

Figure 1 Kaplan-Meier curve showing the cumulative probability of survival at day 90 of patients treated with granulocyte colony-stimulating factor (G-CSF), combination, and standard medical therapy (control). The difference between the 3 groups was statistically significant (P < .001, log-rank test). There was better 90-day survival in the G-CSF group and combination group compared with SMT (P = .0001 and .037, respectively). However, there was no significant difference in 90-day survival between the combination and G-CSF groups (P = .112). NAC, N-acetylcysteine. Clinical Gastroenterology and Hepatology 2018 16, 1650-1656.e2DOI: (10.1016/j.cgh.2018.01.040) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 1 Study design and flow diagram of patients’ selection. G-CSF, granulocyte colony-stimulating factor; NAC, N-acetylcysteine; SMT, standard medical therapy. Clinical Gastroenterology and Hepatology 2018 16, 1650-1656.e2DOI: (10.1016/j.cgh.2018.01.040) Copyright © 2018 AGA Institute Terms and Conditions