Does prior administration of enoxaparin influence the effects of levobupivacaine on blood clotting? Assessment using the Thrombelastograph® S.A. Leonard,

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Presentation transcript:

Does prior administration of enoxaparin influence the effects of levobupivacaine on blood clotting? Assessment using the Thrombelastograph® S.A. Leonard, A. Lydon, M. Walsh, C. Fleming, J. Boylan, G.D. Shorten British Journal of Anaesthesia Volume 86, Issue 6, Pages 808-813 (June 2001) DOI: 10.1093/bja/86.6.808 Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 1 Mean (sd) reaction time (r) in whole blood pre-enoxaparin (S1), whole blood from patients who had received enoxaparin 0.5 mg kg–1 s.c. 12 h previously (bloode)(S2), bloode diluted 50% with saline (S3), bloode/levobupivacaine 2.5 mg ml–1 (S4), bloode/levobupivacaine 2.5 µg ml–1 (S5). See text for significances. British Journal of Anaesthesia 2001 86, 808-813DOI: (10.1093/bja/86.6.808) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 2 Mean (sd) coagulation time (K) in whole blood pre-enoxaparin (S1), whole blood from patients who had received enoxaparin 0.5 mg kg–1 s.c. 12 h previously (bloode)(S2), bloode diluted 50% with saline (S3), bloode/levobupivacaine 2.5 mg ml–1 (S4), bloode/levobupivacaine 2.5 µg ml–1 (S5). See text for significances. British Journal of Anaesthesia 2001 86, 808-813DOI: (10.1093/bja/86.6.808) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 3 Mean (sd) maximum amplitude (MA) in whole blood pre-enoxaparin (S1), whole blood from patients who had received enoxaparin 0.5 mg kg–1 s.c. 12 h previously (bloode)(S2), bloode diluted 50% with saline (S3), bloode/levobupivacaine 2.5 mg ml–1 (S4), bloode/levobupivacaine 2.5 µg ml–1 (S5). See text for significances. British Journal of Anaesthesia 2001 86, 808-813DOI: (10.1093/bja/86.6.808) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 4 Mean (sd) alpha angle (α angle) in whole blood pre-enoxaparin (S1), whole blood from patients who had received enoxaparin 0.5 mg kg–1 s.c. 12 h previously (bloode)(S2), bloode diluted 50% with saline (S3), bloode/levobupivacaine 2.5 mg ml–1 (S4), bloode/levobupivacaine 2.5 µg ml–1 (S5). See text for significances. British Journal of Anaesthesia 2001 86, 808-813DOI: (10.1093/bja/86.6.808) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions