The interaction between weight and family history of total knee replacement with knee cartilage: a 10-year prospective study F. Pan, L. Blizzard, J.

Slides:

Advertisements

Similar presentations

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.

Advertisements

Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis Graeme T. Harding, Cheryl L. Hubley-Kozey,

The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement.

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy P.T. Paradowski, L.S. Lohmander,

Body composition is more closely related to the development of knee osteoarthritis in women than men: a cross-sectional study using the Fifth Korea National.

Associations between proximal tibiofibular joint (PTFJ) types and knee osteoarthritic changes in older adults M. Lu, W. Han, K. Wang, Z. Zhu, B. Antony,

Do NSAIDs Affect Longitudinal Changes in Knee Cartilage Volume and Knee Cartilage Defects in Older Adults? Changhai Ding, MD, Flavia Cicuttini, PhD,

P.T. Paradowski, L.S. Lohmander, M. Englund

Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis V. Silverwood, M. Blagojevic-Bucknall,

The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement.

Velandai K. Srikanth, Ph. D. , Jayne L. Fryer, B. Math. Grad. Dip. Med

Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis M.M. Dowsey, M. Nikpour, P.

Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis X. Wang, F. Cicuttini, X. Jin,

H. A. Kim, I. Kim, Y. W. Song, D. H. Kim, J. Niu, A. Guermazi, M. D

A. J. Teichtahl, A. E. Wluka, Y. Wang, P. N. Wijethilake, B. J

Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis K.M. Beavers, D.P. Beavers,

P.T. Paradowski, L.S. Lohmander, M. Englund

Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants

Women have thinner cartilage and smaller joint surfaces than men after adjustment for body height and weight I.G. Otterness, Ph.D., F. Eckstein, M.D.

Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.

G. M. Goldsmith, D. Aitken, F. M. Cicuttini, A. E. Wluka, T

Sex dimorphism in the association of cardiometabolic characteristics and osteophytes- defined radiographic knee osteoarthritis among obese and non-obese.

Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study K.L. Holliday,

Differences in radiographic features of knee osteoarthritis in African-Americans and Caucasians: the Johnston County Osteoarthritis Project L. Braga,

Differences in trabecular bone texture between knees with and without radiographic osteoarthritis detected by fractal methods P. Podsiadlo, Ph.D., L.

Cross-sectinal and longitudinal associations between serum levels of high sensitivity C- reactive protein, resistin and knee bone marrow lesions in patients.

Maintaining sufficient serum vitamin d levels over two years is associated with improved knee structural and symptomatic outcomes in people with knee.

Time to be positive about negative data?

Osteoarthritis and Cartilage

Psychological factors and their relation to osteoarthritis pain

Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees – data.

Association between body mass index and risk of total knee replacement, the Singapore Chinese Health Study Y.-Y. Leung, J.C. Allen, M. Noviani, L.-W.

S. Muraki, T. Akune, Y. En-yo, M. Yoshida, T. Suzuki, H. Yoshida, H

Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females1 1.

Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression P.T. Paradowski, L.S. Lohmander, M. Englund

M.Y. Chan, J.R. Center, J.A. Eisman, T.V. Nguyen

Quantification of cartilage loss in local regions of knee joints using semi- automated segmentation software: analysis of longitudinal data from the Osteoarthritis.

Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis M. Blagojevic, C. Jinks, A. Jeffery, K.P.

Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.

Who should have a joint replacement? A plea for more ‘phronesis’

Natural history of pain and disability among African–Americans and Whites with or at risk for knee osteoarthritis: A longitudinal study E.R. Vina, D.

Associations between MRI-detected early osteophytes and knee structure in older adults: a population-based cohort study Z. Zhu, L.L. Laslett, W. Han,

A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia D. Dore, BBiotech.(Hons.), C. Ding, M.D., G.

D.J. Hunter Osteoarthritis and Cartilage

The association between hip bone marrow lesions and bone mineral density: a cross- sectional and longitudinal population-based study H. Ahedi, D. Aitken,

A comparison of intra-articular hyaluronan injection accuracy rates between three approaches based on radiographic severity of knee osteoarthritis Y.

S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang

Tibio-femoral cartilage defects 3–5 years following arthroscopic partial medial meniscectomy P.M. Mills, Ph.D., Y. Wang, M.Med., Ph.D., F.M. Cicuttini,

Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group J.A. Zeni, L. Snyder-Mackler Osteoarthritis.

Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis E. Yusuf, J. Bijsterbosch,

Falls risk is associated with pain and dysfunction but not radiographic osteoarthritis in older adults: Tasmanian Older Adult Cohort study S.J. Foley,

Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study L. Busija, R. Buchbinder, R.H. Osborne Osteoarthritis.

Osteoarthritis year 2012 in review: biology

Knee cartilage defects in a sample of older adults: natural history, clinical significance and factors influencing change over 2.9 years J. Carnes, O.

Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen.

Mass effect and signal intensity alteration in the suprapatellar fat pad: associations with knee symptoms and structure J. Wang, W. Han, X. Wang, F.

S. Wei, A. Venn, C. Ding, J. Martel-Pelletier, J. -P. Pelletier, F

D.T. Felson Osteoarthritis and Cartilage

Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: The ROAD study

H. Khan, D. Aitken, C. Ding, L. Blizzard, J. -P. Pelletier, J

Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed A.G. Fischer, E.M. Debbi, A. Wolf

Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis Graeme T. Harding, Cheryl L. Hubley-Kozey,

The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative K.L. Paterson, J.

Effect of a 16 weeks weight loss program on osteoarthritis biomarkers in obese patients with knee osteoarthritis: a prospective cohort study E.M. Bartels,

F. Guillemin, A. C. Rat, B. Mazieres, J. Pouchot, B. Fautrel, L

Association between bone marrow lesions detected by magnetic resonance imaging and knee pain in community residents in Korea I.J. Kim, D.H. Kim, J.Y.

General Information Osteoarthritis and Cartilage

Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years B. Antony, S. Zheng, J. Burgess,

Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis

Presentation transcript:

The interaction between weight and family history of total knee replacement with knee cartilage: a 10-year prospective study F. Pan, L. Blizzard, J. Tian, F. Cicuttini, T. Winzenberg, C. Ding, G. Jones Osteoarthritis and Cartilage Volume 25, Issue 2, Pages 227-233 (February 2017) DOI: 10.1016/j.joca.2016.10.013 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Concurrent associations between category of body mass index and prevalence of medial tibiofemoral cartilage defects at each phase in (A) offspring; (B) controls. The bars represent prevalence of medial tibiofemoral cartilage defects in normal, overweight and obese group (Normal: body mass index < 25; Overweight: 25 ≤ body mass index < 30; Obesity: body mass index ≥ 30). P for trend determined by Kruskal–Wallis test. Osteoarthritis and Cartilage 2017 25, 227-233DOI: (10.1016/j.joca.2016.10.013) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Interaction between weight and time on lateral knee cartilage volume in offspring. There was a significant interaction between weight and time on lateral knee cartilage volume. The effect of increasing weight on lateral knee cartilage volume becomes more negative over time. The model adjusted for common covariates including age, sex, height, smoking, knee injury, radiographic knee OA, bone size and cartilage defects. Osteoarthritis and Cartilage 2017 25, 227-233DOI: (10.1016/j.joca.2016.10.013) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. S1Increase in medial tibiofemoral cartilage defects among those with weight loss, weight stable and weight gain over 10 years. An increase in medial tibiofemoral cartilage defect was defined as an increase of one or greater. Weight loss, weight stable and weight gain were defined as those who lost relative weight change of 5% or greater, those who gained or lost less 5% and those who gained 5%. P for trend determined by Kruskal–Wallis test. Osteoarthritis and Cartilage 2017 25, 227-233DOI: (10.1016/j.joca.2016.10.013) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions