LALCA 2012 Abstracts Journal of Thoracic Oncology

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LALCA 2012 Abstracts Journal of Thoracic Oncology   Journal of Thoracic Oncology  Volume 7, Issue 7, Pages S101-S159 (July 2012) DOI: 10.1097/JTO.0b013e318262df76 Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Patients with lung cancer had a significantly higher hyaluronan levels in sputum than that in the COPD and healthy controls (Log10 scale; p<0.001) B/C – ROC curves for sputum levels of hyaluronan. B- The cut off level of hyaluronan that result in the highest diagnostic accuracy was >31.44ng/mg. The cut-off point of hyaluronan discriminated between healthy controls and lung cancer patients, with 100% specificity and 51% sensitivity. The diagnostic accuracy was 82%. C- The cut-off point of hyaluronan that discriminated COPD and lung cancer patients, with 100% specificity and 33% sensitivity was >48.3ng/mg. The diagnostic accuracy was 69%. Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10. 1097/JTO Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Fig. 1(a) Resected specimen of lobectomy with 4 ribs Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Fig. 1(b) Chest wall reconstruction with Prolene mesh Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Fig. 1 Active air leak. The upper plot (yellow curve), showing air flows, clearly demonstrates an air leak; the lower plot, separately showing the expiratory pressure (”pe“, blue curve) and the inspiratory pressure (”pi“, azure curve), demonstrates an increasing pleural pressures span. Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Fig. 2 Late air leak: a progressive pressure curves divergency anticipates the air leak appearance. In the lower plots we can observe an initial interspace between “pe“ (blue curve) and “pi” (azure curve), then a pressure plateau, and finally a progressive curve divergency since the 2nd post-operative hour. a: the greenish-blue line illustrates the progressive increase of differential pressure (Δp=pe-pi) approximately from the 2nd p.o. day.b: the yellow line shows air flows, revealing an air leakage reappearance, anticipated by the differential pressure increasing. Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Fig. 3 a-b Pleural space effect: high differential pleural pressure without a significant air flow. In both illustrations, referring to a surgical pleurodesis, the lower plots separately show the expiratory (“pe”, blue curve) and inspiratory pressures (“pi”, azure curve), with a wide interspace. In “a”, the upper plot (greenish-blue line) summarizes a high differential pleural pressure (Δp=pe-pi). In “b”, the upper plot (yellow line) describes a sporadic, minimal air flow. Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10. 1097/JTO Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10. 1097/JTO Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10. 1097/JTO Journal of Thoracic Oncology 2012 7, S101-S159DOI: (10.1097/JTO.0b013e318262df76) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions