Yasuyuki Fujita, MD, Yukiko Tsuji-Abe, MD, Kazuko C

Slides:

Advertisements

Similar presentations

Grover disease with a contagious twist

Advertisements

Calcific elastosis in the setting of weight gain

Cutaneous polyarteritis nodosa presenting as a solitary blue toe

Low-dose methotrexate-induced ulcerated psoriatic plaques: A rare case

A 52-year-old man with bullous pemphigoid and bullous cystitis

Systematized linear porokeratosis: A rare variant of diffuse porokeratosis with good response to systemic acitretin Jin-Bon Hong, MD, Cheng-Hsiang Hsiao,

Yul W. Yang, MD, PhD, David J. DiCaudo, MD

Accuracy of biopsy sampling for subtyping basal cell carcinoma

Psoriasis vulgaris with fibrokeratoma from pityriasis amiantacea

Fluoroscopy-induced chronic radiation dermatitis (FICRD) after endovascular abdominal aortic aneurysm endoleak repair Alexis B. Lyons, MS, Valerie M.

Aggressive cutaneous infection with Mycobacterium marinum in two patients receiving anti–tumor necrosis factor-alfa agents Julie Caron, MD, Carine Michot,

Umbilical endometriosis elucidates cause of recurrent pneumothorax

Expression of PD-L1 in mastocytosis

Keratoacanthomas associated with sorafenib therapy

Desmoplastic trichoepithelioma

Jacqueline J. Russo, MD, Keira L. Barr, MD, Larissa Z

Palisaded neutrophilic and granulomatous dermatitis associated with limited systemic sclerosis Basil M. Hantash, MD, PhD, David Chiang, Sabine Kohler,

Diffuse depigmentation in a patient with chronic myeloid leukemia

Negative results of patch testing with standard and textile series in a case of annular lichenoid dermatitis of youth Carlos de la Torre, MD, PhD, Ángeles.

Silica granuloma induced by indwelling catheter

Hypertrophic scars from surgical staples mimicking folliculitis

Volume 4, Issue 2, Pages (March 2018)

Cholangiocarcinoma with skin metastases

Tuberculous cellulitis as a manifestation of miliary tuberculosis in a patient with malignancy-associated dermatomyositis Ji Eun Kim, MD, Joo Yeon Ko,

Clinicopathologic features and T-cell receptor gene rearrangement findings of mycosis fungoides palmaris et plantaris Sang-Tae Kim, MD, Young-Seung Jeon,

Atypical lymphocytic reaction with epidermotropism and lymphocytic vasculopathic reaction (lymphocytic vasculitis) after treatment with imiquimod Jesús.

Mid-dermal elastolysis as a manifestation of immune reconstitution inflammatory syndrome in an HIV-infected patient Carlo Cota, MD, Alessandra Latini,

Serpentine supravenous streaks induced by 5-fluorouracil

Pink pigtails are a clue for the diagnosis of scabies

Rachel L. Kyllo, BS, Mary Kendall Parker, MD, Ilana Rosman, MD, Amy C

A definitive case of metastatic folliculotropic melanoma

Volume 3, Issue 5, Pages (September 2017)

Sanghoon Lee, MD, Sang Gun Park, MD, Min-Geol Lee, MD, PhD

Digital metastasis of tongue squamous cell carcinoma

Cutaneous metastases as the first manifestation of pleural malignant mesothelioma Antonio Maiorana, MD, Federica Giusti, MD, Anna Maria Cesinaro, MD,

Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma Takamasa Ito, MD, Toshifumi Nomura, MD, PhD, Yasuyuki Fujita,

Median raphe cyst on the scrotum and perineum

Histopathological changes in morphea and their clinical correlates: Results from the Morphea in Adults and Children Cohort V Daniel Walker, MD, Joseph.

Scleroderma-like changes in cutaneous eruption of rhabdomyolysis

A survey-based study on nail examinations at an American Academy of Dermatology free skin cancer screening Dayoung Ko, BS, Shari R. Lipner, MD, PhD

Localized cutaneous argyria

Bullous rheumatoid neutrophilic dermatosis

Volume 2, Issue 4, Pages (July 2016)

A new case of neutrophilic sebaceous adenitis: A photodermatosis?

Depression of the frontal veins: A new clinical sign of frontal fibrosing alopecia Sergio Vañó-Galván, MD, PhD, Ana Rita Rodrigues-Barata, MD, Marta Urech,

A case of dermatitis herpetiformis after a mini-gastric bypass surgery

Videodermoscopy of the hyponychium in nail bed psoriasis

Localized nephrogenic fibrosing dermopathy: Aberrant dermal repairing?

Linear IgA disease limited to the oral mucosa

Intradermal injection of autologous platelet-rich plasma for the treatment of vulvar lichen sclerosus Andrew T. Goldstein, MD, Michelle King, MSc, Charles.

Varicella zoster virus–associated generalized pustular psoriasis in a baby with heterozygous IL36RN mutation Kazumitsu Sugiura, MD, PhD, Ryuhei Uchiyama,

Cutaneous sarcoidosis and primary biliary cirrhosis: A chance association or related diseases? Sowmya Kishor, MD, Maria L. Turner, MD, Brian B. Borg,

Linear IgA dermatosis after infliximab infusion for ulcerative colitis

Acute generalized exanthematous pustulosis induced by mifepristone

Hemorrhagic bullae of the oral mucosa

Volume 4, Issue 1, Pages (January 2018)

Lauren R. Penzi, MD, Arturo Saavedra, MD, PhD, Maryanne M. Senna, MD

Quiz Page February 2011 American Journal of Kidney Diseases

Ivanka Kovalyshyn, BA, Amin D. Bijal, MD, Mario E

Disseminated fusarium infection with muscle involvement

Psoriasis vulgaris with fibrokeratoma from pityriasis amiantacea

Marked and restricted cutaneous pigmentation induced by selective intra-arterial cisplatin infusion Teruki Yanagi, MD, Masashi Akiyama, MD, PhD, Satoru.

Transforming growth factor–β overexpression in cutaneous extramedullary hematopoiesis of a patient with myelodysplastic syndrome associated with myelofibrosis

Acanthosis nigricans in a patient with sarcoma of unknown origin

Black dots in palmoplantar warts—challenging a concept: A histopathologic study Isabella Fried, MD, Romano Silvio Kasper, MD, Ivan Hegyi, MD, Werner Kempf,

Chieko Sadahira, MD, Kozo Yoneda, MD, PhD, Yasuo Kubota, MD, PhD

Blue nodule on the finger

Cutaneous polyarteritis nodosa presenting as a solitary blue toe

Atypical pemphigus involving the esophagus with IgG antibodies to desmoglein 3 and IgA antibodies to desmoglein 1 Shigeki Inui, MD, PhD, Masayuki Amagai,

Eosinophilic pustular folliculitis induced by chemotherapy

Presentation transcript:

Nail dystrophy and blisters as sole manifestations in myeloma-associated amyloidosis Yasuyuki Fujita, MD, Yukiko Tsuji-Abe, MD, Kazuko C. Sato-Matsumura, MD, PhD, Masashi Akiyama, MD, PhD, Hiroshi Shimizu, MD, PhD Journal of the American Academy of Dermatology Volume 54, Issue 4, Pages 712-714 (April 2006) DOI: 10.1016/j.jaad.2005.12.031 Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Clinical features and histopathologic findings. A, Brittleness, longitudinal ridging and lamellar splitting of the nail plates were seen on fingernails. B, Biopsy specimen from nail bed of patient's right forefinger demonstrated mild eosinophilic deposits within dermal papilla (arrow). C, Direct fast scarlet staining showed orange amyloid deposits clearly. D, Tense bullae, easily induced by mechanical stimuli, were observed on forearms. E, Biopsy specimen from blister on forearm revealed subepidermal separation and eosinophilic deposits (arrowheads) on superficial dermis. F, Orange deposits were observed beneath bulla and dermal papilla, resistant to potassium-permanganate. (B and E, Hematoxylin-eosin stain; C and F, direct fast scarlet stain; original magnification: B, C, E, F, ×40.) Journal of the American Academy of Dermatology 2006 54, 712-714DOI: (10.1016/j.jaad.2005.12.031) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Fluorescence antigen mapping. A, Antibody directed against type IV collagen (CIV22) mapped to bottom of bulla. B, On top of bulla, antibody against β4 integrin (3E1) was noted at separation of blister roof. (A and B, original magnification ×40.) Journal of the American Academy of Dermatology 2006 54, 712-714DOI: (10.1016/j.jaad.2005.12.031) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions