Fertilization: Monogamy by Mutually Assured Destruction

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Fertilization: Monogamy by Mutually Assured Destruction Mark A. Johnson  Current Biology  Volume 20, Issue 13, Pages R571-R573 (July 2010) DOI: 10.1016/j.cub.2010.05.026 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Interactions between plus (+) and minus (-) gametes leading to fertilization in Chlamydomonas. Current Biology 2010 20, R571-R573DOI: (10.1016/j.cub.2010.05.026) Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 2 Gamete mixing experiments indicate that membrane fusion triggers degradation of HAP2 and FUS1 [1]. (A) Mixing of wild-type gametes results in rapid fusion at mating projections and disappearance of cell-surface FUS1 (black) and HAP2 (red). (B) Adhesion fails when fus1 mutant plus gametes are mixed with wild-type plus gametes and cell-surface HAP2 protein persists. (C) When wild-type plus gametes and hap2 mutant minus gametes are mixed, adhesion occurs, but fusion fails. In this case FUS1 protein persists. Current Biology 2010 20, R571-R573DOI: (10.1016/j.cub.2010.05.026) Copyright © 2010 Elsevier Ltd Terms and Conditions