Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database

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Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database Giovanni Leuzzi, MD, Gaetano Rocco, PhD, Enrico Ruffini, PhD, Isabella Sperduti, MS, Frank Detterbeck, PhD, Walter Weder, MD, Federico Venuta, PhD, Dirk Van Raemdonck, PhD, Pascal Thomas, PhD, Francesco Facciolo, MD The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 1, Pages 47-57.e1 (January 2016) DOI: 10.1016/j.jtcvs.2015.08.034 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Overall (OS), cancer-specific (CSS), and recurrence-free (RFS) survivals of the total sample. B, Cumulative incidence of relapse in the total sample. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 47-57.e1DOI: (10.1016/j.jtcvs.2015.08.034) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, Forest plot of subgroup analysis for adjuvant versus no adjuvant therapy comparison, adjusted for propensity score. B, Distribution of propensity scores. WHO, World Health Organization. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 47-57.e1DOI: (10.1016/j.jtcvs.2015.08.034) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Cancer-specific survival (CSS) according to administration of adjuvant therapy (AT) in the matched sample. SE, Standard error. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 47-57.e1DOI: (10.1016/j.jtcvs.2015.08.034) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 A, Cancer-specific survival (CSS) according to treatment strategy (induction therapy [IT] vs adjuvant therapy [AT]) in the total sample. B, Cancer-specific survival according to the kind of postoperative treatment in the total sample. C and D, Impact of adjuvant therapy on cancer-specific survival according to pT classification in the matched sample. E and F, Impact of adjuvant therapy on cancer-specific survival according to tumor size in the matched. RT, Radiotherapy; SE, Standard error. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 47-57.e1DOI: (10.1016/j.jtcvs.2015.08.034) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Cancer-specific survival according to the use of adjuvant therapy in stage III thymomas. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 47-57.e1DOI: (10.1016/j.jtcvs.2015.08.034) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions