National differences in ulcerative colitis experience and management among patients from five European countries and Canada: An online survey  Stefan Schreiber, Julián Panés, Edouard Louis, Derek Holley, Mandy Buch, Kristine Paridaens  Journal of Crohn's and Colitis  Volume 7, Issue 6, Pages 497-509 (July 2013) DOI: 10.1016/j.crohns.2012.07.027 Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 1 Ulcerative colitis severity rating across countries. (A) Patients' personal classification of ulcerative colitis severity: patients were asked how they would personally describe the severity of their ulcerative colitis overall, regardless of how their doctor described it. (B) Physicians' assessment of ulcerative colitis severity among their caseloads: physicians were asked what percentage of their current ulcerative colitis patients had mild, moderate, or severe disease. The data for each country may not always sum to 100% due to rounding. Journal of Crohn's and Colitis 2013 7, 497-509DOI: (10.1016/j.crohns.2012.07.027) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 2 Mean number of flares experienced (patient-defined), reported to a health care professional, and estimated by physicians (past 12months). Patients were asked how many flare‐ups of their ulcerative colitis they had experienced during the past 12months and how many of these flare‐ups they had discussed with their health care professional. The data for each country may not always sum to 100% due to rounding. Journal of Crohn's and Colitis 2013 7, 497-509DOI: (10.1016/j.crohns.2012.07.027) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 3 Most bothersome factor for patients, as assessed by patients and physicians. (A) Patients were asked which one of the following bothered them the most about their ulcerative colitis: urgency, pain, number of stools per day, blood in your stools, number of tablets to be taken, or none of the above. (B) Physicians were asked which one of the same choices they thought bothered their ulcerative colitis patients the most. The data for each country may not always sum to 100% due to rounding. Journal of Crohn's and Colitis 2013 7, 497-509DOI: (10.1016/j.crohns.2012.07.027) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 4 Patients' descriptions of what remission realistically means. Patients were asked which one of the following statements best described what remission realistically meant for them personally: (1) experiencing no symptoms, feeling similar to how I did before I developed ulcerative colitis; (2) living with some symptoms, but managing life without interruption; (3) living with symptoms and interruptions to daily life, but with less severity, pain, and bleeding as during a flare‐up; and (4) none of these. The data for each country may not always sum to 100% due to rounding. Journal of Crohn's and Colitis 2013 7, 497-509DOI: (10.1016/j.crohns.2012.07.027) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

Figure 5 Estimation of disease control by patients and physicians (last 12months). (A) Patients were asked which one of the following statements best described how effectively their ulcerative colitis had been controlled over the past 12months: (1) my symptoms were completely or mostly under control; (2) my symptoms were present but did not interfere with my quality of life; (3) my symptoms caused some disruption to my quality of life; or (4) my symptoms affected my quality of life on a regular basis. (B) Physicians were asked (in terms of how effectively the patient' ulcerative colitis had been controlled over the last 12months) approximately what percentage of their mild‐to‐moderate ulcerative colitis patients fell into each of the following groups (see above statements). The data for each country may not always sum to 100% due to rounding. Journal of Crohn's and Colitis 2013 7, 497-509DOI: (10.1016/j.crohns.2012.07.027) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions