Volume 135, Issue 2, Pages (August 2008)

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Volume 135, Issue 2, Pages 338-343 (August 2008) The Detection of Flat and Depressed Colorectal Lesions: Which Endoscopic Imaging Approach? David P. Hurlstone Gastroenterology Volume 135, Issue 2, Pages 338-343 (August 2008) DOI: 10.1053/j.gastro.2008.06.027 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 (Left) High-definition white light endoscopy of the distal sigmoid colon in a patient with longstanding quiescent ulcerative colitis. The mucosal area highlighted shows a subtle depressed irregularity. (Center) Methylene blue 0.1% chromoscopy has been applied to the mucosa. A clearly defined flat, depressed lesion is delineated (Paris class 0–IIa + IIc). (Right) Crystal violet (0.05%) chromoscopy has been applied to the lesion and high-magnification imaging acquired at the area of central depression highlighted. The magnification imaging (×100) shows a Kudo type V(a) crypt pattern. Final diagnosis was of a high-grade dysplastic intraepithelial neoplastic lesion. Gastroenterology 2008 135, 338-343DOI: (10.1053/j.gastro.2008.06.027) Copyright © 2008 AGA Institute Terms and Conditions