Effects of newly developed solutions containing trehalose on twenty-hour canine lung preservation Toru Bando, MD, Shinji Kosaka, MD, Chunjiang Liu, MD,

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Effects of newly developed solutions containing trehalose on twenty-hour canine lung preservation Toru Bando, MD, Shinji Kosaka, MD, Chunjiang Liu, MD, Takashi Hirai, MD, Toshiki Hirata, MD, Hiroyasu Yokomise, MD, Kazuyuki Yagi, MD, Kenji Inui, MD, Shigeki Hitomi, MD, Hiromi Wada, MD The Journal of Thoracic and Cardiovascular Surgery Volume 108, Issue 1, Pages 92-98 (July 1994) DOI: 10.5555/uri:pii:S0022522394702241 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 Arterial oxygen tension (PaO 2) of donorand transplanted lungs (mean ± standard error).*p < 0.01, ET-K versus EC; p < 0.05, ET-K versus IT-K.**p < 0.05, ET-K versus EC.FiO 2, Inspired oxygen fraction. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 92-98DOI: (10.5555/uri:pii:S0022522394702241) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 2 Peak inspiratory pressure (PIP) of transplanted lungs(mean ± standard error).*p < 0.05, ET-K versus IT-K;**p < 0.05, ET-K versus IT-K and EC. Preop, Before operation on recipients. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 92-98DOI: (10.5555/uri:pii:S0022522394702241) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 3 Wet/dry weight ratio of transplanted lungs (mean± standard error).*p < 0.01, ET-K versus EC; p < 0.05, ET-K versus IT-K. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 92-98DOI: (10.5555/uri:pii:S0022522394702241) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 4 Representative scanning electron microscopic findings of preserved lungs. Normal canine pulmonary arterial endothelium with intact architecture (D). Scanning electron micrograph of endothelial surface in group A (A) showed almost normal structures preserved. Significant endothelial swelling was evident in group B (B) and disruption of endothelial cell structures in group C (C). (Lines = 10 μm.) The Journal of Thoracic and Cardiovascular Surgery 1994 108, 92-98DOI: (10.5555/uri:pii:S0022522394702241) Copyright © 1994 Mosby, Inc. Terms and Conditions