The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural.

Slides:



Advertisements
Similar presentations
The IASLC Lung Cancer Database Summary of Cases Contributed to Project Total cases submitted 100,869 Excluded from analyses Excluded from analyses19,854.
Advertisements

North American Multicenter Volumetric CT Study for Clinical Staging of Malignant Pleural Mesothelioma: Feasibility and Logistics of Setting Up a Quantitative.
The IASLC Mesothelioma Staging Project: Improving Staging of a Rare Disease Through International Participation  Harvey Pass, MD, Dorothy Giroux, PhD,
The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural.
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the.
Outcome for Patients with Malignant Pleural Mesothelioma Referred for Trimodality Therapy in Western Australia  Arman Hasani, MBBS, FRACP, John M. Alvarez,
Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma at a Large Tertiary Referral Center  Raja M. Flores, MD, Maureen Zakowski, MD, Ennapadam.
The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification.
The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification.
Phase II Clinical Trial of First or Second-Line Treatment with Bortezomib in Patients with Malignant Pleural Mesothelioma  Dean A. Fennell, PhD, FRCP,
The IASLC Lung Cancer Staging Project: A Proposal for a New International Lymph Node Map in the Forthcoming Seventh Edition of the TNM Classification.
The eighth edition TNM stage classification for lung cancer: What does it mean on main street?  Frank C. Detterbeck, MD  The Journal of Thoracic and Cardiovascular.
The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals Regarding the Clinical Staging of Small Cell Lung Cancer.
The IASLC Mesothelioma Staging Project: Proposals for Revisions of the N Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural.
Scientific Advances in Thoracic Oncology 2016
James B. Yu, MD, Lynn D. Wilson, MD, MPH, Frank C. Detterbeck, MD 
Role of Postoperative Radiotherapy in Pathologic Stage IIIA (N2) Non–Small Cell Lung Cancer in a Prospective Nationwide Oncology Outcomes Database  Alex.
The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification.
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the.
The IASLC Lung Cancer Staging Project: External Validation of the Revision of the TNM Stage Groupings in the Eighth Edition of the TNM Classification.
Validation of the Stage Groupings in the Eighth Edition of the TNM Classification for Lung Cancer  Xizhao Sui, MD, Wei Jiang, MD, Haiqing Chen, MD, Fan.
Role of Postoperative Radiotherapy in Pathologic Stage IIIA (N2) Non–Small Cell Lung Cancer in a Prospective Nationwide Oncology Outcomes Database  Alex.
Long-Term Outcome after En Bloc Resection of Non–Small-Cell Lung Cancer Invading the Pulmonary Sulcus and Spine  Stéphane Collaud, MD, MSc, Thomas K.
The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the T component for the Forthcoming (8th) Edition of the TNM Classification of.
The IASLC Lung Cancer Staging Project: Proposals Regarding the Relevance of TNM in the Pathologic Staging of Small Cell Lung Cancer in the Forthcoming.
The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposal for an Evidence- Based Stage Classification System for the Forthcoming (8th) Edition.
The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification.
Gemcitabine and Irinotecan for Patients with Untreated Extensive Stage Small Cell Lung Cancer: SWOG 0119  Wallace Akerley, MD, Jason McCoy, MS, Paul J.
The IASLC Lung Cancer Staging Project: The New Database to Inform the Eighth Edition of the TNM Classification of Lung Cancer  Ramón Rami-Porta, MD, FETCS,
IA05.01 Lung Cancer Cases Journal of Thoracic Oncology
Brian N. Arnold, MD, Daniel C. Thomas, MD, MPH, Joshua E
Supplementary Prognostic Variables for Pleural Mesothelioma: A Report from the IASLC Staging Committee  Harvey I. Pass, MD, Dorothy Giroux, MS, Catherine.
The International Association for the Study of Lung Cancer International Staging Project on Lung Cancer  Peter Goldstraw, MB, FRCS, John J. Crowley, PhD 
Frank Detterbeck, MD  Journal of Thoracic Oncology 
The IASLC Lung Cancer Staging Project: Validation of the Proposals for Revision of the T, N, and M Descriptors and Consequent Stage Groupings in the Forthcoming.
Pleural thickness after neoadjuvant chemotherapy is a prognostic factor in malignant pleural mesothelioma  Masaki Hashimoto, MD, PhD, Jiro Takeuchi, MD,
Frequency of Use and Predictors of Cancer-Directed Surgery in the Management of Malignant Pleural Mesothelioma in a Community-Based (Surveillance, Epidemiology,
Bortezomib (PS-341) in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer: A Southwest Oncology Group Phase II Trial (S0327)  Primo N. Lara,
The IASLC Lung Cancer Staging Project: External Validation of the Revision of the TNM Stage Groupings in the Eighth Edition of the TNM Classification.
The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the.
Frank C. Detterbeck, MD, Andrew G
The Applicability of the Proposed IASLC Staging Revisions to Small Cell Lung Cancer (SCLC) with Comparison to the Current UICC 6th TNM Edition  Sai-Hong.
Ellen Kim, MD, MPH, Siran Koroukian, PhD, Charles R. Thomas, MD 
Thymic carcinoma outcomes and prognosis: Results of an international analysis  Usman Ahmad, MD, Xiaopan Yao, PhD, Frank Detterbeck, MD, James Huang, MD,
The IASLC Lung Cancer Staging Project: Proposals for the Revision of the T Descriptors in the Forthcoming (Seventh) Edition of the TNM Classification.
Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma  Fauzia Shaikh, MD, Marjorie G. Zauderer,
Chemotherapy in Patients ≥80 with Advanced Non-small Cell Lung Cancer: Combined Results from SWOG 0027 and LUN 6  Paul J. Hesketh, MD, Rogerio C. Lilenbaum,
Imaging Requirements in the Practice of Pulmonary Metastasectomy
Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors 
A Multicenter Study of Volumetric Computed Tomography for Staging Malignant Pleural Mesothelioma  Valerie W. Rusch, MD, Ritu Gill, MD, Alan Mitchell,
The IASLC Mesothelioma Staging Project: Improving Staging of a Rare Disease Through International Participation  Harvey Pass, MD, Dorothy Giroux, PhD,
North American Multicenter Volumetric CT Study for Clinical Staging of Malignant Pleural Mesothelioma: Feasibility and Logistics of Setting Up a Quantitative.
The IASLC Lung Cancer Staging Project: Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for.
Multiple Primary Cancers or Multiple Metastases, That Is the Question
The International Association for the Study of Lung Cancer Lung Cancer Staging Project  Hisao Asamura, MD, Kari Chansky, MS, John Crowley, PhD, Peter.
The IASLC Lung Cancer Staging Project: Proposals for the Inclusion of Broncho- Pulmonary Carcinoid Tumors in the Forthcoming (Seventh) Edition of the TNM.
Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma at a Large Tertiary Referral Center  Raja M. Flores, MD, Maureen Zakowski, MD, Ennapadam.
Patterns of Local and Nodal Failure in Malignant Pleural Mesothelioma After Extrapleural Pneumonectomy and Photon-Electron Radiotherapy  Vishal Gupta,
Frequency and Prognostic Significance of Preoperatively Detected Enlarged Regional Lymph Nodes in Patients with Pathological Stage I Non-small Cell Lung.
Clinical and Pathological Staging Validation in the Eighth Edition of the TNM Classification for Lung Cancer: Correlation between Solid Size on Thin-Section.
Andreas Rimner, MD, Kenneth E. Rosenzweig, MD 
Japanese Lung Cancer Registry Study of 11,663 Surgical Cases in 2004: Demographic and Prognosis Changes Over Decade  Noriyoshi Sawabata, MD, PhD, Etsuo.
Stage III Thymic Epithelial Neoplasms are Not Homogeneous with Regard to Clinical, Pathological, and Prognostic Features  Min-Woong Kang, MD, PhD, Eung-Sirk.
Initial Analysis of the International Association For the Study of Lung Cancer Mesothelioma Database  Valerie W. Rusch, MD, Dorothy Giroux, Catherine.
Surveillance Epidemiology and End Results Evaluation of the Role of Surgery for Stage I Small Cell Lung Cancer  James B. Yu, MD, Roy H. Decker, MD, PhD,
Effect of Tumor Size on Prognosis in Patients Treated with Radical Radiotherapy or Chemoradiotherapy for Non–Small Cell Lung Cancer: An Analysis of the.
The IASLC Lung Cancer Staging Project
Visceral Pleural Invasion Classification in Non–Small-Cell Lung Cancer in the 7th Edition of the Tumor, Node, Metastasis Classification for Lung Cancer:
Robert Comis, MD, The Passing of a “Lung Man”
Node-Negative Non-small Cell Lung Cancer: Pathological Staging and Survival in 1765 Consecutive Cases  Benjamin M. Robinson, BSc, MBBS, Catherine Kennedy,
Presentation transcript:

The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma  Anna K. Nowak, M.B.B.S., PhD, Kari Chansky, MS, David C. Rice, MBBCh, Harvey I. Pass, MD, Hedy L. Kindler, MD, Lynn Shemanski, PhD, Andrea Billé, MD, PhD, Robert C. Rintoul, MBChB, PhD, Hasan F. Batirel, MD, PhD, Charles F. Thomas, MD, Joseph Friedberg, MD, Susana Cedres, MD, PhD, Marc de Perrot, MD, MSc, Valerie W. Rusch, MD Peter Goldstraw, Ramón Rami-Porta, Hisao Asamura, David Ball, David Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, John Crowley, Frank Detterbeck, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Dorothy Giroux, Fergus Gleeson, Patti Groome, James Huang, Catherine Kennedy, Jhingook Kim, Young Tae Kim, Laura Kingsbury, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Mirella Marino, Edith M. Marom, Jan van Meerbeeck, Alan Mitchell, Takashi Nakano, Andrew G. Nicholson, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Enrico Ruffini, Valerie Rusch, Nagahiro Saijo, Paul Van Schil, Jean-Paul Sculier, Lynn Shemanski, Kelly Stratton, Kenji Suzuki, Yuji Tachimori, Charles F. Thomas, William Travis, Ming S. Tsao, Andrew Turrisi, Johan Vansteenkiste, Hirokazu Watanabe, Yi-Long Wu, Paul Baas, Jeremy Erasmus, Seiki Hasegawa, Kouki Inai, Kemp Kernstine, Hedy Kindler, Lee Krug, Kristiaan Nackaerts, Harvey Pass, David Rice, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, Kazuya Kondo, Marco Lucchi, Meinoshin Okumura, Eugene Blackstone, H. Asamura, H. Batirel, A. Bille, U. Pastorino, S. Call, A. Cangir, S. Cedres, J. Friedberg, F. Galateau-Salle, S. Hasagawa, K. Kernstine, H. Kindler, B. McCaughan, T. Nakano, A. Nowak, C. Atinkaya Ozturk, H. Pass, M. de Perrot, F. Rea, D. Rice, R. Rintoul, E. Ruffini, V. Rusch, L Spaggiari, D Galetta, K. Syrigos, C. Thomas, J. van Meerbeeck, P. Nafteux, J. Vansteenkiste, W. Weder, I. Optiz, M. Yoshimura Anna K. Nowak, M.B.B.S., PhD, Kari Chansky, MS, David C. Rice, MBBCh, Harvey I. Pass, MD, Hedy L. Kindler, MD, Lynn Shemanski, PhD, Andrea Billé, MD, PhD, Robert C. Rintoul, MBChB, PhD, Hasan F. Batirel, MD, PhD, Charles F. Thomas, MD, Joseph Friedberg, MD, Susana Cedres, MD, PhD, Marc de Perrot, MD, MSc, Valerie W. Rusch, MD Peter Goldstraw, Ramón Rami-Porta, Hisao Asamura, David Ball, David Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, John Crowley, Frank Detterbeck, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Dorothy Giroux, Fergus Gleeson, Patti Groome, James Huang, Catherine Kennedy, Jhingook Kim, Young Tae Kim, Laura Kingsbury, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Mirella Marino, Edith M. Marom, Jan van Meerbeeck, Alan Mitchell, Takashi Nakano, Andrew G. Nicholson, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Enrico Ruffini, Valerie Rusch, Nagahiro Saijo, Paul Van Schil, Jean-Paul Sculier, Lynn Shemanski, Kelly Stratton, Kenji Suzuki, Yuji Tachimori, Charles F. Thomas, William Travis, Ming S. Tsao, Andrew Turrisi, Johan Vansteenkiste, Hirokazu Watanabe, Yi-Long Wu, Paul Baas, Jeremy Erasmus, Seiki Hasegawa, Kouki Inai, Kemp Kernstine, Hedy Kindler, Lee Krug, Kristiaan Nackaerts, Harvey Pass, David Rice, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, Kazuya Kondo, Marco Lucchi, Meinoshin Okumura, Eugene Blackstone, H. Asamura, H. Batirel, A. Bille, U. Pastorino, S. Call, A. Cangir, S. Cedres, J. Friedberg, F. Galateau-Salle, S. Hasagawa, K. Kernstine, H. Kindler, B. McCaughan, T. Nakano, A. Nowak, C. Atinkaya Ozturk, H. Pass, M. de Perrot, F. Rea, D. Rice, R. Rintoul, E. Ruffini, V. Rusch, L Spaggiari, D Galetta, K. Syrigos, C. Thomas, J. van Meerbeeck, P. Nafteux, J. Vansteenkiste, W. Weder, I. Optiz, M. Yoshimura  Journal of Thoracic Oncology  Volume 11, Issue 12, Pages 2089-2099 (December 2016) DOI: 10.1016/j.jtho.2016.08.147 Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 (A) Maximal tumor thickness perpendicular to the chest wall or mediastinum was measured for each of three levels on axial imaging. (B) Measurements of tumor thickness were made on axial slices, representing the upper, middle, and lower third of the hemithorax. These thirds were defined as follows: the upper level extends from the apex of the lung to the inferior margin of the arch of the aorta; the middle level includes the pleura between the upper and lower levels; and the lower level is pleural, including and inferior to the first image on which the left atrium is seen. Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Kaplan-Meier curve for survival by the seventh edition Union for International Cancer Control (UICC) and the American Joint Committee on Cancer T category in cases with T-descriptor support. Clinical staging (A) and pathological staging (B). Abbreviation: MST, median survival time. Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 Kaplan-Meier curve for survival by the proposed eighth edition T category in cases with T-descriptor support. Clinical staging (A), pathological staging (B), and “best” staging (C). Abbreviation: MST, median survival time. Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 1 Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 2A Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 2B Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 2C Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Supplementary Figure 2D Journal of Thoracic Oncology 2016 11, 2089-2099DOI: (10.1016/j.jtho.2016.08.147) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions