Volume 85, Issue 3, Pages (March 2014)

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Volume 85, Issue 3, Pages 522-528 (March 2014) Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport  Catherine K. Yeung, Danny D. Shen, Kenneth E. Thummel, Jonathan Himmelfarb  Kidney International  Volume 85, Issue 3, Pages 522-528 (March 2014) DOI: 10.1038/ki.2013.399 Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 1 Current knowledge of drug-metabolizing enzymes and drug transporters that operate in the human liver, kidney, and intestine. Kidney International 2014 85, 522-528DOI: (10.1038/ki.2013.399) Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 2 Summary of the recognized effects of uremia on drug metabolism and transport. CKD, chronic kidney disease; CYP, cytochrome P450; IL-1, interleukin-1; TNF, tumor necrosis factor. Kidney International 2014 85, 522-528DOI: (10.1038/ki.2013.399) Copyright © 2014 International Society of Nephrology Terms and Conditions

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