Cost-Effectiveness Analysis of Atorvastatin versus Rosuvastatin in Primary and Secondary Cardiovascular Prevention Populations in Brazil and Columbia 

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Cost-Effectiveness Analysis of Atorvastatin versus Rosuvastatin in Primary and Secondary Cardiovascular Prevention Populations in Brazil and Columbia  Joaquín F. Mould-Quevedo, PhD, Magda Vianey Gutiérrez-Ardila, DMD, MSc(c), Jaime Eduardo Ordóñez Molina, MD, PhD, Brett Pinsky, MPH, Nicolás Vargas Zea, MBA, MSc  Value in Health Regional Issues  Volume 5, Pages 48-57 (December 2014) DOI: 10.1016/j.vhri.2014.07.007 Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 1  (A) Treatment decision tree, primary prevention, and (B) Markov health states, primary prevention and secondary prevention models. CV, cardiovascular; CVD, cardiovascular disease. Value in Health Regional Issues 2014 5, 48-57DOI: (10.1016/j.vhri.2014.07.007) Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 2 Discounted total cohort (n = 100) costs for (A) primary and (B) secondary prevention. CVD, cardiovascular disease. Value in Health Regional Issues 2014 5, 48-57DOI: (10.1016/j.vhri.2014.07.007) Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 3 Tornado diagrams, primary prevention, for (A) Colombia A20 versus R10 and (B) Brazil A20 versus R10. A20, atorvastatin 20 mg; CVD, cardiovascular disease; LDL, low-density lipoprotein; LDL-C, low-density lipoprotein cholesterol; QALY, quality-adjusted life-year; R10, rosuvastatin 10 mg. Value in Health Regional Issues 2014 5, 48-57DOI: (10.1016/j.vhri.2014.07.007) Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 4 CE acceptability curves, primary prevention, for (A) Colombia A20 versus R10 and (B) Brazil A20 versus R10. A20, atorvastatin 20 mg; CE, cost-effectiveness; QALY, quality-adjusted life-year; R10, rosuvastatin 10 mg. Value in Health Regional Issues 2014 5, 48-57DOI: (10.1016/j.vhri.2014.07.007) Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions