Volume 54, Issue 1, Pages (July 1998)

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Volume 54, Issue 1, Pages 160-165 (July 1998) Renal cortical mitochondrial aconitase is regulated in hypo- and hypercitraturia  Joel Z. Melnick, Patricia A. Preisig, Orson W. Moe, Paul Srere, Robert J. Alpern  Kidney International  Volume 54, Issue 1, Pages 160-165 (July 1998) DOI: 10.1046/j.1523-1755.1998.00974.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Renal cortical m-aconitase activity: Chronic metabolic acidosis. Following treatment, renal cortical mitochondria were isolated and m-aconitase activity measured. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 M-aconitase protein abundance: chronic metabolic acidosis. Following treatment of the animals, renal cortical mitochondria were isolated and m-aconitase protein abundance was measured by Western blot. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Renal cortical m-aconitase activity: K+ deficiency. Following treatment, renal cortical mitochondria were isolated and m-aconitase activity measured. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 M-aconitase protein abundance: Chronic K+ deficiency. Following treatment of the animals, renal cortical mitochondria were isolated and m-aconitase protein abundance was measured by Western blot. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 5 Renal cortical m-aconitase activity: Chronic alkali feeding. Following treatment, renal cortical mitochondria were isolated and m-aconitase activity measured. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 6 M-aconitase protein abundance: Chronic alkali feeding. Following treatment of the animals, renal cortical mitochondria were isolated and m-aconitase protein abundance was measured by Western blot. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 7 Hepatic m-aconitase activity in chronic metabolic acidosis, K+ deficiency, and alkali feeding. Following treatment, hepatic mitochondria were isolated and m-aconitase activity measured. Kidney International 1998 54, 160-165DOI: (10.1046/j.1523-1755.1998.00974.x) Copyright © 1998 International Society of Nephrology Terms and Conditions