Actin cytoskeleton: Putting a CAP on actin polymerization

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Actin cytoskeleton: Putting a CAP on actin polymerization Victoria A Stevenson, William E Theurkauf Current Biology Volume 10, Issue 19, Pages R695-R697 (October 2000) DOI: 10.1016/S0960-9822(00)00712-0

Fig. 1 The domain structure of CAP. CAP has a highly conserved domain structure. At the amino terminus, CAP has an adenylate cyclase binding domain and a polyproline domain (PP). Within the carboxy-terminal fragment used by Benlali et al.[2] to rescue the CAP mutant phenotype (indicated by underline) are a Verprolin homology domain (VH), an actin monomer-binding domain and a dimerization domain (D). Current Biology 2000 10, R695-R697DOI: (10.1016/S0960-9822(00)00712-0)