Successes and failures of current treatment of heart failure

Slides:

Advertisements

Similar presentations

Dual-site right ventricular and left ventricular pacing in a patient with left ventricular systolic dysfunction and atrial fibrillation using a standard.

Advertisements

The “no reflow” phenomenon following acute myocardial infarction: Mechanisms and treatment options Sanjiv Kaul, MD Journal of Cardiology Volume 64, Issue.

Stage B, a Pre-cursor of Heart Failure Jay N. Cohn, MD, Gary S. Francis, MD Heart Failure Clinics Volume 8, Issue 1, Pages xvii-xviii (January 2012) DOI:

Crohn's disease Prof Daniel C Baumgart, MD, Prof William J Sandborn, MD The Lancet Volume 380, Issue 9853, Pages (November 2012) DOI: /S (12)

Colloquium on Therapy of Right Heart Failure

Volume 357, Issue 9273, Pages (June 2001)

Raynaud's phenomenon The Lancet

Volume 357, Issue 9257, Pages (March 2001)

Pharmacogenetics and future drug development and delivery

Volume 349, Issue 9057, Pages (April 1997)

Volume 376, Issue 9734, Pages (July 2010)

Thank God for Richard Dawkins?

Long-term effects of hormone replacement therapy

Distinctly different purpura on different arms

Recurrent infarction causes the most deaths following myocardial infarction with left ventricular dysfunction Stein Ørn, MD, John G.F. Cleland, MD, Matti.

Paediatric HIV-1 infection

Volume 5, Issue 4, Pages (April 2008)

Volume 376, Issue 9734, Pages (July 2010)

Frailty assessment in elderly people

Long-term effects of hormone replacement therapy

Volume 366, Issue 9486, Pages (August 2005)

A twin with Cushing's disease

Political factors behind US global AIDS programmes slow-down

Step Care Therapy for Hypertension in Diabetic Patients

Body Mass Index and Mortality in Acute Myocardial Infarction Patients

Aspirin in the prevention of cancer – Author's reply

Gene therapy in haematology and oncology

Sexual Activity and Chronic Heart Failure

Drug therapy for coronary heart disease: the Sheffield table

What does STOP-2 tell us about management of hypertension?

Exploring the heart of the human heart

Repeated Heart Rate Measurement and Cardiovascular Outcomes in Left Ventricular Systolic Dysfunction Victoria Hamill, PhD, Ian Ford, PhD, Kim Fox, MD,

Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes:

Gene therapy—where are we?

Self-Management of Anticoagulant Therapy in Mechanical Heart Valve Patients: A Matched Cohort Study Thomas Decker Christensen, MD, PhD, Flemming Skjøth,

INSIGHT and NORDIL The Lancet

Volume 382, Issue 9906, Pages (November 2013)

Organisation of the care of patients with heart failure

Endocardial fibroelastosis of the heart

Incident diabetes in clinical trials of antihypertensive drugs

Meta-analysis of randomised controlled trials

Juan A. Crestanello, MD, Richard C. Daly, MD

HIV myths should not be resuscitated

Volume 352, Pages S15-S18 (October 1998)

Crime, confidentiality, and clinical judgment

Effect of development assistance on domestic health expenditures

Bruce Neal, Fiona Turnbull The Lancet

Volume 362, Pages s6-s7 (December 2003)

Hemifacial sweating after carotid artery dissection

Confessions of a journal junkie

On Statin Treatment to Prevent Sepsis in Dialysis Patients

Volume 371, Issue 9627, Pages (May 2008)

Telling it like it isn't: truth and lies in a post-9/11 world

Volume 382, Issue 9894, Pages (August 2013)

Discussions in Cardiothoracic Treatment and Care: Mechanical Circulatory Support Left Ventricular Assist Device Therapy for Patients With Advanced Heart.

Volume 393, Issue 10167, Pages (January 2019)

C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20 536 patients in the Heart Protection Study Heart Protection.

Thank God for Richard Dawkins?

Department of Error The Lancet Volume 369, Issue 9564, (March 2007)

Volume 361, Issue 9352, Pages (January 2003)

Thank you to our diverse (but not diverse enough) reviewers

Clinical Outcomes After Treatment of Cocaine-Induced Chest Pain with Beta-Blockers: A Systematic Review and Meta-Analysis Kevin Bryan Lo, MD, Hafeez.

Arlene Chan, Marc Buyse, Bin Yao The Lancet Oncology

Costs of eliminating HIV in South Africa have been underestimated

Adjunctive Therapies in the Treatment of Acute Coronary Syndromes

Political factors behind US global AIDS programmes slow-down

Marrick L. Kukin, MD Mayo Clinic Proceedings

Left Ventricular Assist Devices

Clinic attendance and disengagement of young adults with type 1 diabetes after transition of care from paediatric to adult services (TrACeD): a randomised,

β-Blocker Use for the Stages of Heart Failure

Presentation transcript:

Successes and failures of current treatment of heart failure Dr John GF Cleland, MD, Karl Swedberg, MD, Philip A Poole-Wilson, MD The Lancet Volume 352, Pages SI19-SI28 (August 1998) DOI: 10.1016/S0140-6736(98)90015-0 Copyright © 1998 Elsevier Ltd Terms and Conditions

Figure 1 Rule of halves: patients in heart-failure therapy CHF=chronic heart failure; LVD=left ventricular dysfunction. The Lancet 1998 352, SI19-SI28DOI: (10.1016/S0140-6736(98)90015-0) Copyright © 1998 Elsevier Ltd Terms and Conditions

Figure 2 Rule of halves: left ventricular systolic dysfunction The Lancet 1998 352, SI19-SI28DOI: (10.1016/S0140-6736(98)90015-0) Copyright © 1998 Elsevier Ltd Terms and Conditions

Figure 3 Landmark clinical trials of the effects of β-blockers on mortality after myocardial infarction Timolol=Norwegian timolol trial, ref 71; BHAT=β-blocker Heart Attack Study, ref 68; Göteborg=The Göteborg Metoprolol Study, ref 70. The Lancet 1998 352, SI19-SI28DOI: (10.1016/S0140-6736(98)90015-0) Copyright © 1998 Elsevier Ltd Terms and Conditions