Identification of patients at high risk for Clostridium difficile infection: development and validation of a risk prediction model in hospitalized patients.

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Identification of patients at high risk for Clostridium difficile infection: development and validation of a risk prediction model in hospitalized patients treated with antibiotics C.H. van Werkhoven, J. van der Tempel, R. Jajou, S.F.T. Thijsen, R.J.A. Diepersloot, M.J.M. Bonten, D.F. Postma, J.J. Oosterheert Clinical Microbiology and Infection Volume 21, Issue 8, Pages 786.e1-786.e8 (August 2015) DOI: 10.1016/j.cmi.2015.04.005 Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Inclusion flowcharts of cases and controls for derivation and validation studies. Clinical Microbiology and Infection 2015 21, 786.e1-786.e8DOI: (10.1016/j.cmi.2015.04.005) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 2 Performance. (a) ROC curve of simplified risk score in derivation and validation cohort. (b) Calibration of predicted and observed probability of CDI in external validation, zoomed in to show 99.5% of the data. ROC, receiver operating characteristic; AUC, area under the ROC curve. Clinical Microbiology and Infection 2015 21, 786.e1-786.e8DOI: (10.1016/j.cmi.2015.04.005) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions