The impact of allergic rhinitis on bronchial asthma

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Presentation transcript:

The impact of allergic rhinitis on bronchial asthma Jonathan Corren, MD Journal of Allergy and Clinical Immunology Volume 101, Issue 2, Pages S352-S356 (February 1998) DOI: 10.1016/S0091-6749(98)70218-0 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 PC20 values expressed as milligrams per milliliter of methacholine for individual subjects at baseline and after 6 weeks of study. Geometric mean values are denoted by horizontal bars with 95% confidence intervals. Intergroup difference comparing change from baseline, p = 0.022. Adapted with permission from Corren J, et al. J Allergy Clin Immunol 1992;90:250-6. Journal of Allergy and Clinical Immunology 1998 101, S352-S356DOI: (10.1016/S0091-6749(98)70218-0) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Changes in PC20 from baseline 0800 (8 am) at 1200 (12 pm) and 1600 (4 pm) in individual subjects after nasal challenge. Data are expressed in doubling dilutions of methacholine; means are indicated by horizontal bars (n = 10 for both treatments). Adapted with permission from Corren J, et al. J Allergy Clin Immunol 1992;89:611-8. Journal of Allergy and Clinical Immunology 1998 101, S352-S356DOI: (10.1016/S0091-6749(98)70218-0) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Changes of FEV1 after exercise. Exercise was performed with mouth breathing, nasal breathing, and spontaneous breathing. Mean ± SE values are shown. Adapted with permission from Shturman-Ellstein R, et al. Am Rev Resp Dis 1978;118:65-73. Journal of Allergy and Clinical Immunology 1998 101, S352-S356DOI: (10.1016/S0091-6749(98)70218-0) Copyright © 1998 Mosby, Inc. Terms and Conditions