Effects of BAs on BEAS-2B cell viability.

Slides:



Advertisements
Similar presentations
Specificity of production of reactive oxygen species (ROS) against Aspergillus fumigatus conidia by phagocytes from healthy and CF donors. Specificity.
Advertisements

Representation of the 15 selected premature termination codons (PTCs) and their corresponding recoded major protein. Representation of the 15 selected.
Interleukin (IL)-1β-producing cells in peripheral blood mononuclear cells (PBMCs). Interleukin (IL)-1β-producing cells in peripheral blood mononuclear.
The 20-year overall survival was significantly higher in the newborn screening (NBS) group than in the symptoms group for each of the subgroups defined.
Echocardiography view
Bland–Altman plot of projected apnoea threshold of measurement 1 versus 2. a) Rebreathing (R) method (n=20); b) steady-state (SS) method (n=18). Bland–Altman.
Results of the AweScoreCF questionnaire completed by 23 adult cystic fibrosis (CF) patients 1 month before and 3 months after initiating ivacaftor–lumacaftor.
Dose-dependent effect of lipopolysaccharide (LPS) on neutrophil-induced trans-basement membrane migration of eosinophils in healthy volunteers. Dose-dependent.
Dose-dependent effect of lipopolysaccharide (LPS) on neutrophil-induced trans-basement membrane migration of eosinophils in severe asthmatics. Dose-dependent.
Serial imaging while on immunosuppressive therapy (two subjects).
Compliance of the respiratory system (Crs) at baseline and 0 h, 1 h and 2 h following lung volume recruitment. a) Absolute Crs in the respiratory muscle.
Kaplan–Meier curves of 12-month survival after an index chronic obstructive pulmonary disease-related hospitalisation according to level of moderate and.
Distribution of forced expiratory volume in 1 s (FEV1) relative to Global Lung Function Initiative reference values (GLI2012) [10] expressed as FEV1 %
Kaplan–Meier curves for a, b) progression-free survival (PFS) and c, d) overall survival (OS) in a, c) large-cell neuroendocrine carcinoma patients and.
Dried blood spot for therapeutic drug monitoring. a).
Prevalence of true-positive, false-negative and false-positive cases of chronic obstructive pulmonary disease identified with the fixed-limit Global Initiative.
A) CT scan of patient number 1, before pembrolizumab; b) CT scan of patient number 1, after 11 pembrolizumab infusions; c) CT scan of patient number 1,
Survival without tracheostomy
The correlation between Mycobacterium growth indicator tube (MGIT) time to culture positivity (TTP) and bacterial load count by molecular bacterial load.
Influence of do-not-resuscitate (DNR) order specification on overall survival in chronic obstructive pulmonary disease (COPD) patients (log rank test p
Kaplan–Meier curve for the time until the development of lung cancer in patients with idiopathic pulmonary fibrosis. Kaplan–Meier curve for the time until.
A) Exhaled nitric oxide fraction (FeNO) before and after 9 weeks of treatment; b) percentage change in forced expiratory volume in 1 s (FEV1) following.
Distribution of lower extremity artery disease (LEAD) Fontaine stages over the combined chronic obstructive pulmonary disease (COPD) Global Initiative.
Effect of caspase-1 deficiency on lung inflammatory parameters and inflammatory cell subsets in a mouse model of asthma exacerbation. Effect of caspase-1.
Bland–Altman plot of slopes of measurement 1 versus 2
Effects of reslizumab on asthma quality of life questionnaire (AQLQ) score in Global Initiative for Asthma (GINA) Step 4 and 5 patients. Effects of reslizumab.
Change from baseline following beclomethasone/formoterol and placebo in a) platelet–monocyte aggregate formation, b) P-selectin expression and c) platelet.
Lung interleukin (IL)-33 protein expression in vivo depends on caspase-1. Lung interleukin (IL)-33 protein expression in vivo depends on caspase-1. Mice.
Phagocytosis and antifungal activity for phagocytes taken from healthy and CF donors. Phagocytosis and antifungal activity for phagocytes taken from healthy.
Caspase-1 deficient mice have a lower expression of lung T-helper type 2 (Th2)-upstream cytokines at exacerbation. Caspase-1 deficient mice have a lower.
Venn diagram showing the overlap between the various chronic obstructive pulmonary disease (COPD) diagnoses: self-reported physician-diagnosed, fixed ratio.
Cytotoxic activities of polymer micelles containing CFZ in H460 (A) and select micelle formulations in RPMI-8226 (B) cell lines. Cytotoxic activities of.
Cytotoxic effects of PM1 and PM2 empty particle controls and coincubation of CFZ with empty particles tested in H460 (A) and RPMI-8226 (B) cells. Cytotoxic.
In vitro quantification of exon skipping associated with 15 premature termination codons using minigenes. In vitro quantification of exon skipping associated.
A white elephant or the elephant in the room
Swimmer plots showing post-nivolumab progression-free survival for the three main drugs studied according to the line of treatment in which they were received.
Percentage of previously treated tuberculosis (TB) cases with multidrug-resistant (MDR)-TB. Percentage of previously treated tuberculosis (TB) cases with.
Viability and function of mouse pancreatic cell line.
Rhinovirus (RV) infection induces caspase-1 expression in bronchial epithelial cells in asthma. Rhinovirus (RV) infection induces caspase-1 expression.
A–h) Comparison of the effects of cigarette smoke extract (CSE), electronic cigarette (eCig) vapour and IQOS aerosol exposure on a–d) human airway epithelial.
Most frequent words and phrases based on user comments about the registry. Most frequent words and phrases based on user comments about the registry. Word.
Concentration of inflammatory cytokines in epithelial lining fluid (ELF) were plotted for the normal control, smoker normal forced oscillation technique.
Average mean arterial pressure (Pa) during lung volume recruitment (LVR) in (a) the respiratory muscle weakness (RMW) group and (b) the control group.
a) Mortality per time point (p<0
Scatter plot of the % change versus baseline in pulmonary function test results at a) 4 months and b) the end of the study versus the analyte concentration.
Venn diagram showing the overlap between the various spirometric definitions of airway obstruction and respiratory symptoms. **: p
A family-based pulmonary rehabilitation (PR) programme enhanced the coping resources of the families of chronic obstructive pulmonary disease patients.
Measurement of a) IL-8, b) IL-6 and c) GM-CSF release by BEAS-2B cells stimulated with deoxycholic acid for 48 h. Measurement of a) IL-8, b) IL-6 and c)
The regression lines between the asynchrony index (AI) and the double true index (DTI) shown for overall data, and for mask and helmet separately. The.
Forest plot of adjusted odds ratios (with 95% confidence intervals) from multivariable multinomial logistic regression analysis (table 4), by number of.
Relationship between bronchodilator response of physiological parameters and concentration of interleukin (IL)-8 in epithelial lining fluid (ELF). Relationship.
Concordance of review article recommendations with contemporary guidelines. Concordance of review article recommendations with contemporary guidelines.
Α1-Antitrypsin (AAT) therapy considerations: a) practical difficulties with AAT infusions; b) concerns regarding AAT doses >60 mg·kg−1 per week. α1-Antitrypsin.
Weekly pneumococcal community-acquired pneumonia incidence rates over 5 years, with delineated school holiday periods by year. a) Year 1 (September 2008–2009).
Interleukin-1 blockade effects interferon (IFN)-γ production by multiple cell types. a) Gating strategy for flow cytometry: CD56+ natural killer (NK) cells.
Physician perspectives on the most useful methods for monitoring α1-antitrypsin deficiency in the clinical trial setting versus clinical practice. Physician.
Differences in a) functional residual capacity (FRC) and b) lung clearance index (LCI) when using all trials in comparison with only the first two trials.
Scatter plot of body mass index (BMI) versus forced expiratory volume in the first second (FEV1), and linear correlation lines for normal spirometry and.
Percentage of women using snus and/or cigarette smoke during pregnancy based on self-reported time for stopping from those who completed both 18-week and.
Physician perspectives on self-administration of i. v. α1-antitrypsin
Distribution of patients in the first- or second-year follow-up according to the number of acute exacerbations of chronic obstructive pulmonary disease.
Post-operative a) neutrophil counts, but not b) lymphocyte or c) platelet counts, were higher in current smokers than ex-smokers. #: time-points were statistically.
Percentage of culture-positive or PCR-positive sputum samples at stable state and exacerbation in year 1 and year 2 (full cohort, year 1 or year 2). a)
Primary human airway smooth muscle cells were stimulated with different concentrations of a, e) 18 mg·mL−1 nicotine tobacco-flavoured e-cigarette vapour.
Composition of the most common clusters at the a) onset of the first acute respiratory tract infection (swab A) and b) 3 weeks later (swab B) illustrated.
Comparison of cancer-specific survival in patients with nonsmall cell lung cancer detected incidentally by computed tomography (CT) (n=41) or chest radiography.
Percentage of positive results by pathogen among study patients with identified pathogens. “Other” includes respiratory viruses, Stenotrophomonas, Prevotella,
Curcumin decreases viability and proliferation of Bcr-Abl-expressing cells. Curcumin decreases viability and proliferation of Bcr-Abl-expressing cells.
Change in intracellular concentration of microRNA (miR)-17 in NuLi-1 bronchial epithelial cells (BECs) treated with miR-17-loaded lipid–polymer hybrid.
Effect of lipoxin A4 (LXA4) on alveolar type II cell (ATII) wound repair. Effect of lipoxin A4 (LXA4) on alveolar type II cell (ATII) wound repair. LXA4.
Presentation transcript:

Effects of BAs on BEAS-2B cell viability. Effects of BAs on BEAS-2B cell viability. BEAS-2B cell viability following stimulation with a) lithocholic, b) deoxycholic, c) cholic and d) chenodeoxycholic acids at varying concentrations. Viability is measured as a percentage of vehicle control after 48 h exposure. Data are presented as mean±sem. Negative controls were measured by fixing the cells in methanol before adding the TiterBlue and MTT reagent (n=6). C: control; CTB: CellTiter-Blue assay; MTT: thiazolyl blue tetrazolium bromide. **: p=0.01; ****: p<0.0001 versus controls. Adil Aldhahrani et al. ERJ Open Res 2017;3:00107-2016 ©2017 by European Respiratory Society