Volume 136, Issue 4, Pages e2 (April 2009)

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Presentation transcript:

Volume 136, Issue 4, Pages 1215-1224.e2 (April 2009) Alcohol Consumption and the Risks of Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus Nirmala Pandeya, Gail Williams, Adèle C. Green, Penelope M. Webb, David C. Whiteman Gastroenterology Volume 136, Issue 4, Pages 1215-1224.e2 (April 2009) DOI: 10.1053/j.gastro.2008.12.052 Copyright © 2009 AGA Institute Terms and Conditions

Figure 1 Plots for dose effect (in logit scale) of average lifetime alcohol consumption on (A) EAC, (B) EGJAC, and (C) ESCC using a generalized additive model with 3 degrees of freedom smoothing spline function adjusted for age, sex, body mass index (BMI) 1 year ago, frequency of heartburn or acid reflux, education, frequency of aspirin use in the past 5 years, and smoking. Gastroenterology 2009 136, 1215-1224.e2DOI: (10.1053/j.gastro.2008.12.052) Copyright © 2009 AGA Institute Terms and Conditions

Supplementary Figure 1 Plots for dose effect (in logit scale) of average lifetime alcohol consumption on ESCC among (A) never smokers, (B) former smokers, and (C) current smokers using a generalized additive model with 3 degrees of freedom smoothing spline function adjusted for age, sex, body mass index 1 year ago, frequency of heartburn or acid reflux, education, and frequency of aspirin use in the past 5 years. Gastroenterology 2009 136, 1215-1224.e2DOI: (10.1053/j.gastro.2008.12.052) Copyright © 2009 AGA Institute Terms and Conditions

Supplementary Figure 2 Dose-response effect of lifetime consumption of (A) beer and (B) liqueur on ESCC using a generalized additive model with 3 degrees of freedom smoothing spline function adjusted for age, sex, body mass index 1 year ago, frequency of heartburn or acid reflux, education, frequency of aspirin use in the past 5 years, and smoking. Gastroenterology 2009 136, 1215-1224.e2DOI: (10.1053/j.gastro.2008.12.052) Copyright © 2009 AGA Institute Terms and Conditions

Supplementary Figure 3 Plots for dose effect (in logit scale) of average lifetime wine consumption on (A) EAC, (B) EGJAC, and (C) ESCC using a generalized additive model with 3 degrees of freedom smoothing spline function adjusted for age, sex, body mass index 1 year ago, frequency of heartburn or acid reflux, education, frequency of aspirin use in the past 5 years, and smoking. Gastroenterology 2009 136, 1215-1224.e2DOI: (10.1053/j.gastro.2008.12.052) Copyright © 2009 AGA Institute Terms and Conditions