Sally C. Morton, PhD, Paul G. Shekelle, MD, PhD, John L

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Presentation transcript:

Antimicrobial prophylaxis for urinary tract infection in persons with spinal cord dysfunction Sally C. Morton, PhD, Paul G. Shekelle, MD, PhD, John L. Adams, PhD, Carol Bennett, MD, Bruce H. Dobkin, MD, John Montgomerie, MBChB, Barbara G. Vickrey, MD, MPH Archives of Physical Medicine and Rehabilitation Volume 83, Issue 1, Pages 129-138 (January 2002) DOI: 10.1053/apmr.2002.26605 Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 1 Flowchart of studies. *Specific reasons for exclusion are given in table 1. Archives of Physical Medicine and Rehabilitation 2002 83, 129-138DOI: (10.1053/apmr.2002.26605) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 2 Any-antimicrobial versus no-antimicrobial pooled analysis presented as a shrinkage plot in which the individual comparison and pooled rate differences are shown, along with CIs. The studies are ordered by quality score from highest (top) to lowest (bottom) and alphabetized for studies with the same score. The rectangle for each comparison is that comparison’s individual difference in weekly infection rates, treatment minus control. The horizontal line through the rectangle indicates the 95% CI for the individual comparison. The vertical line at 0 breaks the effect size range into effect sizes indicating that treatment is favored (ie, <0) or that the control condition is favored (ie, >0). The diamond at the bottom of the graph labeled “Overall” shows the location of the pooled or overall estimate. (■, individual comparison effect size, horizontal line is 95% CI; ♦, pooled effect size, symbol width is 95% CI.) (A) Symptomatic infections in acute patients; the overall CI is to the left of 0 and crosses 0, which indicates a nonsignificant decrease in infection rate (<90d post-SCI). (B) Symptomatic infections in nonacute patients; the overall CI is to the left of 0 and crosses 0, indicating a nonsignificant decrease in the symptomatic infection rate. (C) Asymptomatic infections in acute patients; the overall CI is to the left of 0 and does not cross 0, indicating a significant decrease in the asymptomatic infection rate. (D) Asymptomatic infections in nonacute patients; the overall CI just crosses 0, indicating that the decrease in the asymptomatic infection rate approaches statistical significance. Archives of Physical Medicine and Rehabilitation 2002 83, 129-138DOI: (10.1053/apmr.2002.26605) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions