Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label,

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Presentation transcript:

Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label, pragmatic, randomised controlled trial Neal Navani, PhD, Matthew Nankivell, MSc, David R Lawrence, FRCS, Sara Lock, FRCP, Himender Makker, FRCP, Prof David R Baldwin, FRCP, Richard J Stephens, Prof Mahesh K Parmar, PhD, Prof Stephen G Spiro, FRCP, Prof Stephen Morris, PhD, Prof Sam M Janes, PhD The Lancet Respiratory Medicine Volume 3, Issue 4, Pages 282-289 (April 2015) DOI: 10.1016/S2213-2600(15)00029-6 Copyright © 2015 Navani et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 Trial profile EBUS-TBNA=endobronchial ultrasound-guided transbronchial needle aspiration. EUS-FNA=endoscopic ultrasound-guided fine needle aspiration. NSCLC=non-small-cell lung cancer. The Lancet Respiratory Medicine 2015 3, 282-289DOI: (10.1016/S2213-2600(15)00029-6) Copyright © 2015 Navani et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Time to treatment decision in all patients (A) and in those with non-small-cell lung cancer (B) Kaplan-Meier plots for (A) all patients and (B) patients with non-small-cell lung cancer only undergoing CDS or EBUS-TBNA. CDS=conventional diagnosis and staging. NSCLC=non-small-cell lung cancer. EBUS-TBNA=endobronchial ultrasound-guided transbronchial needle aspiration. HR=hazard ratio. The Lancet Respiratory Medicine 2015 3, 282-289DOI: (10.1016/S2213-2600(15)00029-6) Copyright © 2015 Navani et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 3 Overall survival of patients with non-small-cell lung cancer Survival of patients with non-small-cell lung cancer undergoing CDS or EBUS-TBNA. NSCLC=non-small-cell lung cancer. CDS=conventional diagnosis and staging. EBUS-TBNA=endobronchial ultrasound-guided transbronchial needle aspiration. HR=hazard ratio. The Lancet Respiratory Medicine 2015 3, 282-289DOI: (10.1016/S2213-2600(15)00029-6) Copyright © 2015 Navani et al. Open Access article distributed under the terms of CC BY Terms and Conditions