Supplemental Figure 2. Probiotics failed to increase enterocyte migration and proliferation in rotavirus-infected underweight mice. A, Immunohistochemistry for BrdU at different times after injection. Graphs show mean position (+ SD) of foremost and least-progressed BrdU-labeled enterocytes (n = 7 mice per group). B, Proliferation of crypt cells, determined 4 hours post-BrdU (n = 15 mice per group; mean + SD). C, Crypt height at various times post-BrdU (n = 7 mice per group; mean + SD); hpi, hours post-injection; dpi, days post-injection; L. reuteri strains were designated as 17938 and 6475; all images captured at 200X magnification.
A PBS 17938 6475 4 hpi 24 hpi 2 dpi 3 dpi 4 dpi B C