A Progressive Postresection Walking Program Significantly Improves Fatigue and Health-Related Quality of Life in Pancreas and Periampullary Cancer Patients

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Presentation transcript:

A Progressive Postresection Walking Program Significantly Improves Fatigue and Health-Related Quality of Life in Pancreas and Periampullary Cancer Patients Theresa P. Yeo, PhD, MPH, MSN, AOCNP, Sherry A. Burrell, RN, CNE, ACNS-BC, Patricia K. Sauter, MSN, ACNP, Eugene P. Kennedy, MD, FACS, Harish Lavu, MD, FACS, Benjamin E. Leiby, PhD, Charles J. Yeo, MD, FACS Journal of the American College of Surgeons Volume 214, Issue 4, Pages 463-475 (April 2012) DOI: 10.1016/j.jamcollsurg.2011.12.017 Copyright © 2012 American College of Surgeons Terms and Conditions

Figure 1 Flow diagram of study participants. Of the 165 potentially eligible patients, 118 were approached for study inclusion, 110 were enrolled, and data were sufficient for analysis in 102 patients. Journal of the American College of Surgeons 2012 214, 463-475DOI: (10.1016/j.jamcollsurg.2011.12.017) Copyright © 2012 American College of Surgeons Terms and Conditions

Figure 2 Basic design of the study. After randomization, the patients were allocated to either the intervention group or the usual care group. (FFS, FACIT-Fatigue Scale; FVAS, Fatigue Visual Analog Scale; PPC, pancreas and periampullary cancer; PVAS, Pain Visual Analog Scale; SF-36v2, Short Form-36v2 questionnaire.) Journal of the American College of Surgeons 2012 214, 463-475DOI: (10.1016/j.jamcollsurg.2011.12.017) Copyright © 2012 American College of Surgeons Terms and Conditions

Figure 3 Example of the graduated walking prescription given to patients allocated randomly to the intervention group. Journal of the American College of Surgeons 2012 214, 463-475DOI: (10.1016/j.jamcollsurg.2011.12.017) Copyright © 2012 American College of Surgeons Terms and Conditions

Figure 4 (A) Kaplan-Meier overall survival curves for the Intervention Group (solid line, n = 54) and the Usual Care Group (dashed line, n = 48) for all patients with resected pancreatic and periampullary adenocarcinoma. Median survival has not been reached in either group, and the curves are not significantly different. Time zero is the date of resection. (B) Kaplan-Meier overall survival curves for the Intervention Group (solid line, n = 50) and the Usual Care Group (dashed line, n = 43) for patients with resected pancreatic adenocarcinoma. Median survival has not been reached in either group, and the curves are not significantly different. Time zero is the date of resection. Journal of the American College of Surgeons 2012 214, 463-475DOI: (10.1016/j.jamcollsurg.2011.12.017) Copyright © 2012 American College of Surgeons Terms and Conditions