What's New in PAH?.

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Presentation transcript:

What's New in PAH?

Program Themes

Important Advances in PAH

Evolution of Clinical Trials in PAH

Challenges With Clinical Trial Design

Growing Use of Combination Therapy

AMBITION Trial: Ambrisentan and Tadalafil in Patients With PAH

Trends in Treatment Options for a Newly Diagnosed Patient in WHO FC II or III

AMBITION Trial: First Adjudicated Clinical Failure by Subgroups

Determinants of Prognosis in PAH

GRIPHON Trial Design

GRIPHON Trial Clinical Efficacy

GRIPHON Trial Treatment Effect by Subgroup

Effective Communication With Patients

Pharmacologic Agents for PAH 3 Pathways

Initial Triple Therapy

Opportunity to Incorporate PROs

PAH-SYMPACT

World Symposium on Pulmonary Hypertension, February 2018

Perspectives of 2 Experts

Concluding Remarks

Abbreviations