Effectiveness and Cost-effectiveness of Measuring Fecal Calprotectin in Diagnosis of Inflammatory Bowel Disease in Adults and Children Zhuo Yang, Nick.

Slides:

Advertisements

Similar presentations

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta- analysis Eline J.C.A. Kamp, John S. Kane, Alexander C. Ford Clinical Gastroenterology.

Advertisements

MiraLAX Is Not as Effective as GoLytely in Bowel Cleansing Before Screening Colonoscopies Michael Hjelkrem, Joel Stengel, Mark Liu, David P. Jones, Stephen.

Risk of Neoplasia After Colectomy in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis Lauranne A.A.P. Derikx, Loes H.C.

Prevalence and Lifetime Risk of Endoscopy-related Complications Among Patients With Inflammatory Bowel Disease Jason Ferreira, Mona Akbari, Laurie Gashin,

Agreement Between Home-Based Measurement of Stool Calprotectin and ELISA Results for Monitoring Inflammatory Bowel Disease Activity Anke Heida, Mariska.

An Unusual Cause of Small Bowel Obstruction: A Plastic Glove

Millie D. Long, Bruce E. Sands

Agreement Between Home-Based Measurement of Stool Calprotectin and ELISA Results for Monitoring Inflammatory Bowel Disease Activity Anke Heida, Mariska.

Gauree Gupta, Ebbing Lautenbach, James D. Lewis

A Shocking Cystory Clinical Gastroenterology and Hepatology

Portal Hypertensive Enteropathy in Small-Bowel Capsule Endoscopy

Immune Reconstitution Inflammatory Syndrome of the Small Bowel in a Human Immunodeficiency Virus–Negative Patient Severin Daum, Christoph Loddenkemper,

Right Upper Quadrant Pain and a Normal Abdominal Ultrasound

Prevalence of Irritable Bowel Syndrome–type Symptoms in Patients With Celiac Disease: A Meta-analysis Anita Sainsbury, David S. Sanders, Alexander C.

Trends in Overall and Cause-Specific Mortality Among Patients With Inflammatory Bowel Disease From 1982 to 2010 Tine Jess, Morten Frisch, Jacob Simonsen

Patient-Reported Outcome Measures for Use in Clinical Trials and Clinical Practice in Inflammatory Bowel Diseases: A Systematic Review Marin J. de Jong,

Rebekah S. Wieland, Richard S. Zubarik, Maryam J. Zenali

Wireless Capsule Endoscopy Fragmentation in a Patient With Crohn's Disease Marcia Henriques de Magalhães Costa, Andre da Luz Moreira, Cyrla Zaltman Clinical.

Negative Effects on Psychological Health and Quality of Life of Genuine Irritable Bowel Syndrome–type Symptoms in Patients With Inflammatory Bowel Disease

An Unusual Cause of Small Bowel Obstruction: A Plastic Glove

Granular Cell Tumor in Colonic Polyp Found on Screening Colonoscopy

Clinical Features, Treatment, and Survival of Patients With Colorectal Cancer With or Without Inflammatory Bowel Disease Raja Affendi Raja Ali, Cara.

Endoscopy 20 Years Into the Future

Eighty-Year-Old Patient With History of a Twelve Millimeter Adenomatous Polyp Resected at Age of Seventy-Five Years David Lieberman Clinical Gastroenterology.

Diffuse Large B-Cell Lymphoma of the Small Bowel as an Unusual Cause for Recurrent Obscure Gastrointestinal Bleeding: Diagnosis by Video Capsule Endoscopy

Activity-Based Costing and Management in a Hospital-Based GI Unit

Risk of Nonmelanoma Skin Cancer in Patients With Inflammatory Bowel Disease Who Use Thiopurines Is Not Increased Fiona D.M. van Schaik, Martijn G.H.

Michael Hjelkrem, Joel Stengel, Mark Liu, David P. Jones, Stephen A

Cainan Foltz, Williamson Strum

Traveling Internationally: Avoiding and Treating Travelers' Diarrhea

Amie L. Harvey, Tommy Yen, Anand Kunda

AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review Jean-Frederic Colombel,

When Should Screening Stop for Elderly Individuals at Average and Increased Risk for Colorectal Cancer? Folasade P. May, Samir Gupta Clinical Gastroenterology.

Millie D. Long, Hans H. Herfarth, Clare A. Pipkin, Carol Q

Leon P. McLean, Jonathan S. Chun, Raymond K. Cross

Metastatic Malignant Melanoma of the Gastrointestinal Tract

Reenu Malhotra, Kevin Turner, Amnon Sonnenberg, Robert M. Genta

Endoscopic Ultrasound–Guided Cholecystoduodenostomy for Acute Cholecystitis in a Patient With Thrombocytopenia and End-Stage Liver Disease Awaiting Transplantation

Dushyant Singh, Reetu Singh, Wendell K. Clarkston

Cesare Hassan, Emilio Di Giulio, Perry J

Prevalence and Lifetime Risk of Endoscopy-related Complications Among Patients With Inflammatory Bowel Disease Jason Ferreira, Mona Akbari, Laurie Gashin,

Peter Bytzer Clinical Gastroenterology and Hepatology

Rebecca M. Lovell, Alexander C. Ford

Colonoscopy Identifies Increased Prevalence of Large Polyps or Tumors in Patients 40– 49 Years Old With Hematochezia vs Other Gastrointestinal Indications

Effects of Different Coping Strategies on Physical and Mental Health of Patients With Irritable Bowel Syndrome Lilian Dindo, PhD Clinical Gastroenterology.

Risk of Cerebrovascular Accidents and Ischemic Heart Disease in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis Siddharth.

Issue Highlights Clinical Gastroenterology and Hepatology

Volume 140, Issue 6, Pages e2 (May 2011)

Risk of Cancer in Patients With Inflammatory Bowel Diseases: A Nationwide Population- based Cohort Study With 30 Years of Follow-up Evaluation Michael.

Ethnicity Influences Phenotype and Outcomes in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Studies Hai Yun.

Nicolas Williet, William J. Sandborn, Laurent Peyrin–Biroulet

Javier Oliver, Blanca Rueda, Miguel A

Temporal Trends in Initiation of Therapy With Tumor Necrosis Factor Antagonists for Patients With Inflammatory Bowel Disease: A Population-based Analysis

Meenakshi Bewtra, Chinyu Su, James D. Lewis

Patrícia Andrade, Susana Lopes, Guilherme Macedo

A 27-Year-Old Woman With Constipation: Diagnosis and Treatment

Coagulation in Liver Disease: A Guide for the Clinician

Issue Highlights Clinical Gastroenterology and Hepatology

Issue Highlights Clinical Gastroenterology and Hepatology

Coloduodenal Fistula in Crohn’s Disease

Rintaro Hashimoto, Akimichi Chonan

Adverse Outcomes: Why Bad Things Happen to Good People

Medical Therapy for Refractory Pediatric Crohn’s Disease

Issue Highlights Clinical Gastroenterology and Hepatology

Rintaro Hashimoto, Akimichi Chonan

Metastatic Malignant Melanoma of the Gastrointestinal Tract

Klaus Mönkemüller, Helmut Neumann, Lucia C. Fry

Jordan E. Axelrad, Sharyle A. Fowler, Sonia Friedman, Ashwin N

Thiopurines and Risk of Colorectal Neoplasia in Patients With Inflammatory Bowel Disease: A Meta-analysis Tine Jess, Anthony Lopez, Mikael Andersson,

Choosing Wisely and the Perceived Drivers of Endoscopy Use

Presentation transcript:

Effectiveness and Cost-effectiveness of Measuring Fecal Calprotectin in Diagnosis of Inflammatory Bowel Disease in Adults and Children Zhuo Yang, Nick Clark, K.T. Park Clinical Gastroenterology and Hepatology Volume 12, Issue 2, Pages 253-262.e2 (February 2014) DOI: 10.1016/j.cgh.2013.06.028 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 Overview of model structure. (A) Model 1 and (B) Model 2. *Endoscopy = upper endoscopy and colonoscopy with histopathology. Clinical Gastroenterology and Hepatology 2014 12, 253-262.e2DOI: (10.1016/j.cgh.2013.06.028) Copyright © 2014 AGA Institute Terms and Conditions

Figure 2 One-way sensitivity analysis. Clinical Gastroenterology and Hepatology 2014 12, 253-262.e2DOI: (10.1016/j.cgh.2013.06.028) Copyright © 2014 AGA Institute Terms and Conditions

Figure 3 PSA. Acceptability curves from the 3000 independent simulations. Panels A and B show FCS strategy decreases in cost-effectiveness at higher WTP. Panels C and D show that FCS at low FC cutoff values have a wider range of WTP (between 2 vertical hurdles) in which FCS at 50 μg/g is more likely cost-effective than FCS at 100 μg/g (between the left hurdle and the origin). Clinical Gastroenterology and Hepatology 2014 12, 253-262.e2DOI: (10.1016/j.cgh.2013.06.028) Copyright © 2014 AGA Institute Terms and Conditions

Figure 4 Three-way sensitivity analysis for using FC assay in pediatric group. ICER of DEE strategy at different pre-test probabilities of true IBD, as compared with FCS strategy. Clinical Gastroenterology and Hepatology 2014 12, 253-262.e2DOI: (10.1016/j.cgh.2013.06.028) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 1 Three-way sensitivity analysis for using FC assay in adult group: FC sensitivity, specificity, and proportion of true IBDs among suspected adult IBD patients. The 4 charts show the color-coded map of ICER of DEE strategy at different pre-test probabilities of true IBD, as compared with FCS strategy. The hollow squares indicate the base-case sensitivity and specificity of FCS in the adult group. Clinical Gastroenterology and Hepatology 2014 12, 253-262.e2DOI: (10.1016/j.cgh.2013.06.028) Copyright © 2014 AGA Institute Terms and Conditions