Figure 1 Treat to target, remission and low disease activity in SLE

Slides:



Advertisements
Similar presentations
The Patient Experience With Systemic Lupus Erythematosus
Advertisements

Systemic Lupus Erythematosus
Figure 3 The induction of anti-DNA antibodies by bacterial DNA
Figure 1 Lymphocytes during the disease
of different experimental arthritis models
Figure 3 Connexins in cartilage
Figure 5 Involvement of B cells in SLE
Figure 4 The theoretical contribution of genetic and
Figure 1 Historical evolution of the clinical classification and
Figure 2 A timeline summarizing the development of diagnostic tools in rheumatology Figure 2 | A timeline summarizing the development of diagnostic tools.
Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.
Nat. Rev. Nephrol. doi: /nrneph
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Induction of immune tolerance
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 2 Heat map of targeted therapies in autoimmune diseases
Figure 1 Organs involved in coeliac-disease-associated autoimmunity
Figure 2 Targeted versus untargeted metabolomics approaches
Figure 1 Metabolic profiling as a tool for studying rheumatic diseases
Figure 1 Schematic comparison of expected
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 4 Antinuclear antibodies and disease activity in SLE
Figure 3 Transcriptome studies performed in the target
Figure 2 Shared genetic loci in systemic autoimmune diseases
Figure 3 Nucleic acid sensors in SLE
Nat. Rev. Rheumatol. doi: /nrrheum
Time between systemic lupus erythematosus (SLE) and haematological malignancy diagnoses. Time between systemic lupus erythematosus (SLE) and haematological.
Disease activity over time in autoantibody-positive patients treated with belimumab. Disease activity over time in autoantibody-positive patients treated.
Supplementary Figure 1. Longitudinal study in a representative number of SLE patients one year before (t1), at the time (t2), and one year after renal.
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 4 Approaches to targeting inhibitory immune receptors
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 2 Overlap of associated loci among five rheumatic diseases
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 3 Statistical approaches for the analysis of metabolomic data
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 3 Summary of overall survival by Kaplan–Meier
Figure 3 Multi-hit model for autoimmune diseases
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Overview of biosimilar product development
Nat. Rev. Nephrol. doi: /nrneph
Management of Systemic Lupus Erythematosus
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 The current model of the pathogenesis of SLE
Figure 1 Reproductive health in patients with rheumatic diseases
Figure 1 Principles for the diagnosis and management of osteoarthritis
Mean Safety of Estrogens in Lupus Erythematosus National Assessment–Systemic Lupus Erythematosus Disease Activity Index (SELENA-SLEDAI) score at the last.
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Chronic inflammation and DNA damage in people with SLE
Figure 3 Nuclear-penetrating autoantibodies and synthetic lethality
Figure 1 Overall worldwide prevalence ranges for SLE
Figure 2 Cellular contributions to the development of SLE
Optimizing Outcomes for Patients With Systemic Lupus Erythematosus: Key Considerations.
Figure 2 Phenotypes of osteoarthritis
Figure 2 Proposed approach to treating myositis-associated interstitial lung disease Figure 2 | Proposed approach to treating myositis-associated interstitial.
Figure 1 Differential effects of bone-forming agents on bone surfaces
Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Patterns of joint and organ involvement in rheumatic disease
Figure 2 The main effects of adipokines on bone remodelling in osteoarthritis Figure 2 | The main effects of adipokines on bone remodelling in osteoarthritis.
Longitudinal changes in serum G3BP concentrations and SLEDAI in 15 patients with SLE. Each plot represents one patient. Longitudinal changes in serum G3BP.
Celiac disease as a model for SLE
Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum
Presentation transcript:

Figure 1 Treat to target, remission and low disease activity in SLE Figure 1 | Treat to target, remission and low disease activity in SLE. Control of active disease in systemic lupus erythematosus (SLE) can be conceived as concentric circles of progressively improving treatment response states associated with stepwise improvements in outcome, representing a continuum along which treatment can be directed. Rates of damage accrual will be lower at each stage of disease control, theoretically reaching zero for complete off-treatment remission. LLDAS, lupus low disease activity state. Morand, E. F. (2016) Remission in SLE — are we there yet? Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2016.174