3D cold-plate electrospun silk fibroin nanofibers

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Presentation transcript:

3D cold-plate electrospun silk fibroin nanofibers Colby Thomas

Need to Know Basic architecture of skin: outer epidermis layer that contains keratinocytes serves as a barrier to infection dermis layer thick and contains fibroblasts and extracellular matrix mainly comprising collagen provides a strength, flexibility and networks systems for body homeostasis.

What Is It? Three techniques for creating nanofiber materials: self-assembly phase separation electrospinning Three types: traditional electrospinning (TE) salt leaching electrospinning (SLE) cold plate electrospinning

Why do we need CPE? Must be able to use biocompatible nanomaterials High porosity without sacrificing stability 3D thick structure Keep up with artificial skin and organ deficit demands

Future Outlook Can be used to treat skin deformities Can help treat conditions such as diabetic stomach ulcers Provides a new way to look at skin regeneration and further application