Volume 380, Issue 9849, Pages (October 2012)

Slides:

Advertisements

Similar presentations

Crohn's disease Prof Daniel C Baumgart, MD, Prof William J Sandborn, MD The Lancet Volume 380, Issue 9853, Pages (November 2012) DOI: /S (12)

Advertisements

Towards universal access to HIV prevention, treatment, care, and support: the role of tuberculosis/HIV collaboration Alasdair Reid, MD, Fabio Scano,

Volume 384, Issue 9961, Pages (December 2014)

Chee-Seng Tan, MRCP, David Gilligan, FRCPE, Dr Simon Pacey, FRCP

Food, livestock production, energy, climate change, and health

Volume 376, Issue 9755, Pages (November 2010)

Volume 387, Issue 10022, Pages (March 2016)

HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study

Volume 6, Issue 7, Pages (July 2005)

The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis Dr Michael Roerecke, PhD, Prof Janusz Kaczorowski,

Volume 355, Issue 9221, Pages (June 2000)

Volume 359, Issue 9322, Pages (June 2002)

Pharmacogenetics and future drug development and delivery

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort.

Global funding trends for malaria research in sub-Saharan Africa: a systematic analysis Dr Michael G Head, PhD, Sian Goss, MSc, Yann Gelister, MSc, Victor.

Authorship trends in The Lancet Global Health

Volume 2, Issue 4, Pages e151-e158 (April 2015)

Volume 387, Issue 10022, Pages (March 2016)

Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: a systematic review and meta-analysis Katharina Kranzer,

Meta-analysis of randomised controlled trials

Volume 5, Issue 4, Pages (April 2006)

Volume 371, Issue 9611, Pages (February 2008)

Country, regional, and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis Christian Løvold Storhaug, MS, Svein.

Estimating trends in life expectancy in HIV-positive individuals

Volume 2, Issue 12, Pages e530-e539 (December 2015)

Volume 366, Issue 9499, Pages (November 2005)

Global funding trends for malaria research in sub-Saharan Africa: a systematic analysis Dr Michael G Head, PhD, Sian Goss, MSc, Yann Gelister, MSc, Victor.

Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes:

Volume 374, Issue 9707, Pages (December 2009)

Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1·9 million participants

Volume 382, Issue 9895, Pages (September 2013)

Volume 391, Issue 10121, Pages (February 2018)

Mortality and causes of death in people diagnosed with HIV in the era of highly active antiretroviral therapy compared with the general population: an.

Volume 9, Issue 10, Pages (October 2008)

Incident diabetes in clinical trials of antihypertensive drugs

National, regional, and global prevalence of smoking during pregnancy in the general population: a systematic review and meta-analysis Shannon Lange,

Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz.

HIV myths should not be resuscitated

Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: a systematic review and meta-analysis Ulla Beijer, PhD, Achim Wolf, MSc, Dr.

Estimation of national, regional, and global prevalence of alcohol use during pregnancy and fetal alcohol syndrome: a systematic review and meta-analysis

Effect of development assistance on domestic health expenditures

HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic.

Volume 4, Issue 10, Pages e433-e441 (October 2017)

Volume 351, Pages S8-S11 (June 1998)

Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review

Amanda Rojek, MBBS, Prof Peter Horby, FRCP, Dr Jake Dunning, MRCP

Trends in infant mortality in Venezuela between 1985 and 2016: a systematic analysis of demographic data Jenny García, MSc, Prof Gerardo Correa, MSc,

Authorship trends in The Lancet Global Health

Risk of poor development in young children in low-income and middle-income countries: an estimation and analysis at the global, regional, and country.

Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000–2016: A Pooled Sequence Analysis Benjamin Chimukangara,

Confessions of a journal junkie

Pre-entry screening programmes for tuberculosis in migrants to low-incidence countries: a systematic review and meta-analysis Dr Robert W Aldridge, MSc,

Population coverage of artemisinin-based combination treatment in children younger than 5 years with fever and Plasmodium falciparum infection in Africa,

Volume 372, Issue 9647, Pages (October 2008)

Volume 2, Issue 6, Pages e243-e251 (June 2015)

Volume 393, Issue 10172, Pages (February 2019)

Volume 6, Issue 2, Pages e116-e127 (February 2019)

Volume 393, Issue 10172, Pages (February 2019)

Forecasting the care needs of the older population in England over the next 20 years: estimates from the Population Ageing and Care Simulation (PACSim)

Tobacco use among people living with HIV: analysis of data from Demographic and Health Surveys from 28 low-income and middle-income countries Dr Noreen.

Volume 3, Issue 9, Pages e431-e440 (September 2016)

Volume 371, Issue 9614, Pages (March 2008)

Primary prophylaxis of cryptococcal disease with fluconazole in HIV-positive Ugandan adults: a double-blind, randomised, placebo-controlled trial Dr.

Thank you to our diverse (but not diverse enough) reviewers

Volume 377, Issue 9777, Pages (May 2011)

Costs of eliminating HIV in South Africa have been underestimated

Population attributable fractions for risk factors for dementia in low-income and middle- income countries: an analysis using cross-sectional survey data

The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis Dr Michael Roerecke, PhD, Prof Janusz Kaczorowski,

Volume 371, Issue 9611, Pages (February 2008)

Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling Gwenan M Knight, PhD, C Finn McQuaid,

Presentation transcript:

Volume 380, Issue 9849, Pages 1250-1258 (October 2012) Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis Ravindra K Gupta, MRCP, Michael R Jordan, MD, Binta J Sultan, MRCP, Andrew Hill, PhD, Daniel HJ Davis, MRCP, John Gregson, MSc, Anthony W Sawyer, PhD, Raph L Hamers, MD, Nicaise Ndembi, PhD, Prof Deenan Pillay, FRCP, Dr Silvia Bertagnolio, MD The Lancet Volume 380, Issue 9849, Pages 1250-1258 (October 2012) DOI: 10.1016/S0140-6736(12)61038-1 Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 1 Countries contributing data by regions and subregions The Lancet 2012 380, 1250-1258DOI: (10.1016/S0140-6736(12)61038-1) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 2 Study selection The Lancet 2012 380, 1250-1258DOI: (10.1016/S0140-6736(12)61038-1) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 3 Prevalence of drug resistance in treatment-naive trial participants with HIV-1, by time since antiretroviral rollout (A) East Africa. (B) Southern Africa. (C) West and central Africa. (D) Latin America and the Caribbean. Every circle is a study and the size of the circle is proportional to the precision of the estimate from the individual study, with sizes comparable within individual graphs only. The trend line is predicted prevalence. The Lancet 2012 380, 1250-1258DOI: (10.1016/S0140-6736(12)61038-1) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 4 Prevalence of major drug-resistance mutations that confer resistance to non-nucleoside reverse transcriptase inhibitors, by time since antiretroviral rollout in east Africa Size of circle is proportional to the precision of the estimate from the individual study, with sizes comparable within individual graphs only. The trend line is predicted prevalence. DRM=drug-resistance mutation. NNRTI=non-nucleoside reverse transcriptase inhibitor. The Lancet 2012 380, 1250-1258DOI: (10.1016/S0140-6736(12)61038-1) Copyright © 2012 Elsevier Ltd Terms and Conditions