Whole body [18F]fluorodeoxyglucose positron emission tomography imaging for the diagnosis of pacemaker or implantable cardioverter defibrillator infection:

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Presentation transcript:

Whole body [18F]fluorodeoxyglucose positron emission tomography imaging for the diagnosis of pacemaker or implantable cardioverter defibrillator infection: a preliminary prospective study L. Bensimhon, T. Lavergne, F. Hugonnet, J.-L. Mainardi, C. Latremouille, C. Maunoury, A. Lepillier, J.-Y. Le Heuzey, M. Faraggi Clinical Microbiology and Infection Volume 17, Issue 6, Pages 836-844 (June 2011) DOI: 10.1111/j.1469-0691.2010.03312.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Plot of standard uptake value of [18F]fluorodeoxyglucose uptake around boxes between controls (group 2, left) and patients (group 1, right). A maximal standard uptake value (SUVmax) threshold value equal to or >2.2 completely separates controls (left) and non-infected patients on the one hand (right column below the marker) and infected patients on the other hand. Clinical Microbiology and Infection 2011 17, 836-844DOI: (10.1111/j.1469-0691.2010.03312.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Box infection. Top: transverse (left), sagittal (medium) and coronal (right) positron emission tomography slices through the box. High [18F]fluorodeoxyglucose uptake indicates pocket infection. Bottom: corresponding computed tomography slices. Clinical Microbiology and Infection 2011 17, 836-844DOI: (10.1111/j.1469-0691.2010.03312.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 Physiological uptake around the box (control patient). Top: transverse (left), sagittal (medium) and coronal (right) positron emission tomography slices through the box. The mild [18F]fluorodeoxyglucose uptake is usual and does not indicate any infectious process. Bottom: corresponding computed tomography slices. SUV, standard uptake value. Clinical Microbiology and Infection 2011 17, 836-844DOI: (10.1111/j.1469-0691.2010.03312.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 4 Lead infection. Top: transverse (left), sagittal (medium) and coronal (right) slices displaying a focal hot spot on a lead (circle), indicating lead infection. Bottom: corresponding computed tomography slices. Clinical Microbiology and Infection 2011 17, 836-844DOI: (10.1111/j.1469-0691.2010.03312.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 5 Physiological lead aspect. Top: transverse (left), sagittal (medium) and coronal (right) slices displaying a non-infected lead (circle). Bottom: corresponding computed tomography slices. Clinical Microbiology and Infection 2011 17, 836-844DOI: (10.1111/j.1469-0691.2010.03312.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions