Simple LOA A B Cascading LOA X A Y B Z Blanket LOA A Company 1 (donor) Company 2 (recipient) ‘Company 1 gives permission to Cefas to use the data they hold for “product A” to allow company 2 in support of registration for their “product B”.’ NOTE: -this does not allow company 2 to then provide letters of access to other companies that might want to use product B in their formulations. A B Cascading LOA ‘Company 1 gives permission to Cefas to use the data they hold for “product A” to allow company 2 in support of registration for their “product B”, and all downstream users thereof.’ NOTE: - this allows company 2 to then provide letters of access to other companies that might want to use product B in their formulations. Downstream LOAs become Company 2’s responsibility. Company 1 (donor) Company 2 (recipient) Company 3 (downstream user) X A B Company 4 (downstream user) Y Company 5 (downstream user) Z Blanket LOA Company 1 (donor) Company 2 (recipient) B ‘Company 1 gives permission to Cefas to use the data they hold for “product A” to allow company 2 in support of registration of any of their products.’ NOTE: -this does not allow company 2 to then provide letters of access to other companies (downstream users) that might want to use company 2’s products in their formulations containing company 1’s product. A