A. Kurz, T. Kopyeva, I. Suliman, A. Podolyak, J. You, B. Lewis, C

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Presentation transcript:

Supplemental oxygen and surgical-site infections: an alternating intervention controlled trial A. Kurz, T. Kopyeva, I. Suliman, A. Podolyak, J. You, B. Lewis, C. Vlah, R. Khatib, A. Keebler, R. Reigert, M. Seuffert, L. Muzie, S. Drahuschak, E. Gorgun, L. Stocchi, A. Turan, D.I. Sessler British Journal of Anaesthesia Volume 120, Issue 1, Pages 117-126 (January 2018) DOI: 10.1016/j.bja.2017.11.003 Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 1 Flow chart. British Journal of Anaesthesia 2018 120, 117-126DOI: (10.1016/j.bja.2017.11.003) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 2 Box plot of average oxygen concentration during surgery in the 80% and 30% target oxygen groups. The first quartile, median, and third quartile comprise the boxes; whiskers extend to the most extreme observations within 1.5 times the inter-quartile range of the first and third quartiles, respectively. British Journal of Anaesthesia 2018 120, 117-126DOI: (10.1016/j.bja.2017.11.003) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 3 Relative risk of having the primary composite outcome of 30-day mortality and major infection-related complications in 80% vs 30% oxygen within levels of selected factors: type of surgery, age, colorectal resection vs other surgeries, age <60 vs ≥60 yr, BMI, current smoker vs ex-/never smoker, ASA physical status, primary diagnosis (cancer vs others), and laparoscopic vs open surgery. The significance criterion was 0.0036 for each comparison (i.e. 0.05/14), and thus 99.6% CIs are plotted. None of the interactions between the treatment and these factors on the primary outcome was significant at the 5% level. British Journal of Anaesthesia 2018 120, 117-126DOI: (10.1016/j.bja.2017.11.003) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions