Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study Prof Andy C Rawstron, PhD,

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Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study Prof Andy C Rawstron, PhD, Aloysius Ssemaganda, MSc, Ruth de Tute, PhD, Chi Doughty, PhD, Darren Newton, PhD, Anna Vardi, PhD, Paul A S Evans, PhD, Kostas Stamatopoulos, MD, Roger G Owen, MRCP, Tracy Lightfoot, PhD, Katie Wakeham, PhD, Alex Karabarinde, Gershim Asiki, PhD, Dr Robert Newton, PhD The Lancet Haematology Volume 4, Issue 7, Pages e334-e340 (July 2017) DOI: 10.1016/S2352-3026(16)30192-2 Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Prevalence of MBL in the Ugandan and UK cohorts, by B-cell phenotype (A) Proportion of participants with detectable CLL-type MBL and CD5-negative MBL according to the 2005 diagnostic criteria.22 (B) Proportion of participants with a monoclonal B-cell subset. CLL=chronic lymphocytic leukaemia. MBL=monoclonal B-cell lymphocytosis. The Lancet Haematology 2017 4, e334-e340DOI: (10.1016/S2352-3026(16)30192-2) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Absolute monoclonal B-cell count, by phenotype CLL=chronic lymphocytic leukaemia. MBL=monoclonal B-cell lymphocytosis. The Lancet Haematology 2017 4, e334-e340DOI: (10.1016/S2352-3026(16)30192-2) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 3 LAIR1 expression pattern in monoclonal CD5-negative B cells MBL=monoclonal B-cell lymphocytosis. The Lancet Haematology 2017 4, e334-e340DOI: (10.1016/S2352-3026(16)30192-2) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions