Figure 1 Biospecimen handling pipeline

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Figure 1 Biospecimen handling pipeline Figure 1 | Biospecimen handling pipeline. Establishing standard operating procedures for collection and handling of samples and data is a critical first step in ensuring high-quality translational research. Preanalytical variables can affect various steps of the pipeline, from specimen collection to downstream analysis. Key preanalytical variables include those relating to the patient's individual physiology (green), the uniformity of biospecimen collection (blue) and biospecimen handling procedures (pink). Quality control assays can highlight sample adequacy, confirm optimal sample processing and/or storage and predict the validity of downstream analysis. Yeung, R. S. M. et al. (2016) Enhancing translational research in paediatric rheumatology through standardization Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2016.156