The CAT(2) Comes Back Cell Host & Microbe

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The CAT(2) Comes Back Cell Host & Microbe Musoki Mwimba, Xinnian Dong  Cell Host & Microbe  Volume 21, Issue 2, Pages 125-127 (February 2017) DOI: 10.1016/j.chom.2017.01.012 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 A Model Showing How SA Binding to CATALASE2 Represses Auxin and JA Biosynthesis to Strengthen Plant Immunity against Biotrophic Pathogens In the absence of biotrophic pathogens, CAT2 efficiently converts H2O2 to H2O. Upon exposure to biotrophic pathogens, SA accumulates and binds to CAT2 to inhibit its enzymatic activity. The accumulating H2O2 sulfenylates TSB1 to repress IAA production. SA binding to CAT2 also blocks CAT2’s role in facilitating JA biosynthesis through ACX. The resulting reduction in IAA and JA levels strengthens plant immunity against biotrophic pathogens. Cell Host & Microbe 2017 21, 125-127DOI: (10.1016/j.chom.2017.01.012) Copyright © 2017 Elsevier Inc. Terms and Conditions