Rats (open cycle), HFD rats (open triangle) and DM rats (solid cycle)

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Rats (open cycle), HFD rats (open triangle) and DM rats (solid cycle) Figure 3 Simvastatin depletion in rat hepatic microsomes (A), 1-hydroxymidazolam formation from midazolam in rat hepatic microsomes (B) and the corresponding Eadie-Hofstee plots (C), and uptake of simvastatin (D) by hepatocytes of CON Rats (open cycle), HFD rats (open triangle) and DM rats (solid cycle) Figure legends Dan Xu1, 2 et al. Acta Pharmacol Sin 2014; 35: 1215–1225; doi: 10.1038/aps.2014.39 Published by © 2014 CPS and SIMM

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