Rewriting History: Fever of Unknown Origin Jenna R. Bordelon, BS, Syeda U. Abbas, MD, Arsalan Q. Shabbir, MD, PhD, Andrew L. Ross, MD  The American Journal of Medicine  Volume 128, Issue 9, Pages 956-958 (September 2015) DOI: 10.1016/j.amjmed.2015.05.006 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 The patient had a hyperpigmented, indurated, warm, exquisitely tender plaque on the external right buttock and the posteriolateral thigh. The American Journal of Medicine 2015 128, 956-958DOI: (10.1016/j.amjmed.2015.05.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 T1-weighted magnetic resonance imaging of the pelvis with contrast enhancement and fat suppression demonstrated a heterogeneous appearance within the soft tissues surrounding the buttocks. This was representative of an intense inflammatory process. Numerous areas of signal void were consistent with silicone deposits. The American Journal of Medicine 2015 128, 956-958DOI: (10.1016/j.amjmed.2015.05.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 3 A biopsy sample of the indurated plaque was stained with hematoxylin and eosin. A, A granulomatous inflammatory infiltrate was seen in the reticular dermis, bar = 200 μm. B, Clear, nonbirefringent vacuoles were visualized at the inferior portion of the specimen consistent with silicone, bar = 200 μm. C, Magnification highlighted vacuoles with a Swiss-cheese-like appearance, 50 μm. The American Journal of Medicine 2015 128, 956-958DOI: (10.1016/j.amjmed.2015.05.006) Copyright © 2015 Elsevier Inc. Terms and Conditions