Volume 143, Issue 1, Pages (January 2013)

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Volume 143, Issue 1, Pages 14-18 (January 2013) Change in Sweat Chloride as a Clinical End Point in Cystic Fibrosis Clinical Trials Anthony G. Durmowicz, MD, Kimberly A. Witzmann, MD, Curtis J. Rosebraugh, MD, MPH, Badrul A. Chowdhury, MD, PhD CHEST Volume 143, Issue 1, Pages 14-18 (January 2013) DOI: 10.1378/chest.12-1430 Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 1 Scatter plots of absolute change from baseline in % predicted FEV1 vs absolute change from baseline in sweat chloride at wk 24 in patients treated with ivacaftor for trial 1 (adolescent/adult) and trial 2 (children). (Adapted from Center for Drug Evaluation and Research.9) CHEST 2013 143, 14-18DOI: (10.1378/chest.12-1430) Copyright © 2013 The American College of Chest Physicians Terms and Conditions