ExPASy (Expert Protein Analysis System)

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Presentation transcript:

ExPASy (Expert Protein Analysis System) David Shiuan Department of Life Science, Institute of Biotechnology and Interdisciplinary Program of Bioinformatics National Dong Hwa University

Proteomics and sequence analysis tools Proteomics [PeptIdent, PeptideMass, ...] DNA -> Protein [Translate] Similarity searches [BLAST] Pattern and profile searches [ScanProsite] Post-translational modification and topology prediction Primary structure analysis [ProtParam, pI/MW, ProtScale] Secondary and tertiary structure prediction [SWISS-MODEL, Swiss-PdbViewer] Alignment [T-COFFEE, SIM] Biological text analysis

Potential O-GlcNAC

SUMO (Small Ubiquitin-Like Modifier) SUMO is member of ubiquitin and ubiquitin-like superfamily Most SUMO proteins contain tetrapeptide motif B-K-x-D/E, where B is a hydrophobic residue, K is lysine and D/E is an acidic residue Substrate specificity is derived from ubc9 and the respective substrate motif

nnpredict Result