High resolution oesophageal manometry High resolution oesophageal manometry. a) The trace shows a normal pattern of oesophageal contraction descending with preceding opening of the lower oesophageal sphincter. b) Lack of lower oesophageal sphincter tone in a patients with chronic cough. c) Fail... High resolution oesophageal manometry. a) The trace shows a normal pattern of oesophageal contraction descending with preceding opening of the lower oesophageal sphincter. b) Lack of lower oesophageal sphincter tone in a patients with chronic cough. c) Failed peristalsis with accumulation of food and secretions causing increase in pressure. Alyn H. Morice Breathe 2013;9:256-266 ©2013 by European Respiratory Society